جستجوی مقالات مرتبط با کلیدواژه « سیستم ایمنی هومورال » در نشریات گروه « پزشکی »

Clinical findings show that stress can gradually affect the activity of various systems of the body such as immune system and impair them. Different variables potentiate and modify this effect. This research aimed at studying the relationship of personality traits (self-respect, tenacity, type A personality), stress, and stress coping skills with immune system status in nurses. In this descriptive-analytical study, 246 individuals were selected by simple random sampling method. At the first stage, the subjects on the job completed the questionnaires of self-respect, tenacity, type A personality, stress, and stress coping skills. At the second stage to determine the amount of antibodies, 2-cc blood of the subjects was assessed. The data were analyzed using correlational methods. The findings indicated a significant, positive and meaningful relationship of immunoglobulin antibody with “self-respect”, and IgM antibody with “type A personality” in male nurses (p<0.05). But there was no significant relationship between the immune system variables and tenacity, stress, and stress coping skills. From among the predictive variables (self-respect, tenacity, type A personality, stress, and stress coping skills) only the stress variable had significant relationship with the criterion variable (IgA antibody)(p=0.05). Regarding the results it can be said that self-respect may adjust IgG variable in stress positions (especially in chronic stress). So in hard jobs such as nursing, psychological characteristics should be considered as an important job factor along with physical capabilities.

Saffron (crocus sativus L.), an important spice rich in carotenoids, is used in folk medicine to treat numerous diseases. This study examines the effects of saffron consumption on innate and humoral immunity of healthy male students.

41 healthy volunteered university students in two control and case groups were included in this study and consumed respectively milk and milk containing saffron for 6 weeks. Blood samples were collected from the subjects at weeks 0, 3 and 6. Innate immunity was evaluated by determining the percentage and counts of monocytes, neutrophils, eosinophils, basophils, platelets and the total white cells, CRP concentration and C3 and C4 concentrations and humoral immunity was assessed by deterning the percentage of lymphocytes and the concentrations of IgG, IgM and IgA.

Three weeks after saffron consumption, monocytes percentage and IgG concentration increased significantly (P<0.05, P=0.01). Total white blood cells and platelets count also reduced significantly (P<0.05). After 6 weeks, monocytes percentage and IgG concentration reduced significantly (P<0.05, P< 0.001) and platelets count increased significantly (P<0.05) as compared with week 3.

This investigation demonstrated that saffron consumption enhances innate and humoral immunity systems and has anti-inflammatory effects. These effects depending on the duration of saffron consumption.