جستجوی مقالات مرتبط با کلیدواژه « مکمل خرفه » در نشریات گروه « پزشکی »

Diabetes and obesity are among the main problems of societies, and the main preventable causes of death all over the world. Also, type 2 diabetes is more common in obese people, and obesity itself causes some degree of insulin resistance. The aim of the present study was to investigate the effect of an eight-week aerobic training plus a supplement of Portulaca Oleracea seed on metabolic syndrome factors in middle-aged men with Diabetes Type 2 on the threshold of obesity.

In this experimental study, 40 male patients with type 2 diabetes with an average age of 40-65 and BMI between 28 and 30, were selected and then randomly placed into four groups of control (10 people), exercise + placebo (10 people), supplement (10 people), and exercise + supplement (10 people). Lack of a history of regular sports activity and lack of consumption of Portulaca oleracea plant (for the previous 6 months) were controlled. Also, people who had chronic cardiovascular diseases or chronic inflammation, diabetic foot ulcers and hepatitis, as well as people who took vitamin supplements and smoked, were excluded from the study. The training groups had 3 training sessions per week, in the first week, each session lasted for 30 minutes, and in the eighth week, it was changed to 45 minutes of walking without rest with an intensity equal to 50 to 70% of the maximum reserve heart rate. Supplemental groups consumed 5.7 grams of purslane capsules after lunch and dinner daily. The control group was not subjected to any training or supplements during the 8 weeks. Correlated t-test was used to examine intra-group differences, and analysis of covariance was used to examine inter-group differences at a significant level of P<0.05 using SPSS version 26 software.

The results of covariance analysis showed a significant difference in lipid profile values and fasting sugar levels in the three experimental groups compared to the control group (P<0.05).

Probably, the consumption of Portulaca oleracea seed supplement and aerobic exercise improves the lipid profile and fasting sugar in middle-aged men with type 2 diabetes. Therefore, it is recommended for middle-aged men with type 2 diabetes on the verge of obesity to take purslane seed supplement and aerobic exercise.

The aim of this study was to investigate the effect of eight weeks of high-intensity interval training (HIIT) and Portulaca Oleracea extract on FGF-21 levels and insulin resistance in rats with NAFLD.

Twenty male Wistar rats at six weeks old and 160 to 185 g weight were randomly divided into four groups: fatty liver control, HIIT, Portulaca Oleracea extract, and HIIT+Portulaca Oleracea extract. According to the weight of the mice, Portulaca Oleracea supplement with a dose of 400 mg/kg was given to the two respective groups. The HIIT training protocol was performed for 8 weeks, 5 sessions per week, and each session was performed at 80-90% of maximum speed. Hepatic FGF21 level and insulin resistance were measured after 8 weeks of HIIT training and consumption of purslane extract. One-way analysis of variance and Tukey's post hoc test were used to compare groups at a significance level of p<0.05.

Insulin resistance in HIIT (P=0.005), Portulaca Oleracea extract (P=0.011), and HIIT+Portulaca Oleracea extract (P=0.002) groups were significantly lower than fatty liver control group. The level of liver FGF-21 in the HIIT (p=0.023), Portulaca Oleracea extract (p=0.005) and HIIT+ Portulaca Oleracea extract (p=0.001) groups was significantly higher than the fatty liver control group.

It seems that HIIT and Portulaca Oleracea extract could improve insulin resistance in NAFLD by increasing FGF-21 levels and can play an important role in controlling the progress of this disease.

the aim of this study was to investigate the effect of eight weeks of high intensity interval training (HIIT) and Portulaca Oleracea extract on chemerin level and insulin resistance in rats with NAFLD. Twenty five male Wistar rats were randomly divided into five groups: healthy control, fatty liver control, HIIT, Portulaca Oleracea extract, and HIIT+Portulaca Oleracea extract. To induce NAFLD, the rats were fed a high-fat diet for 12 weeks. Portulaca Oleracea supplement at 400 mg/kg was given to the experimental groups. HIIT was performed for 8 weeks, 5 sessions per week with 7 repetitions of 1 minute at 90% maximum speed accompanied by active rest intervals including 2 minutes of running at 20% maximum speed. Hepatic chemerin level and insulin resistance were measured after 8 weeks of HIIT and consumption of purslane extract. Insulin resistance was significantly higher in fatty liver control group than healthy controls (P=0.002). But it was significantly lower in HIIT group (P=0.01), Portulaca Oleracea extract (P=0.037), and HIIT+Portulaca Oleracea extract group (P=0.012) than that in fatty liver control group. Chemerin levels in the HIIT group (p=0.01), Portulaca Oleracea extract (p=0.017) and HIIT+ Portulaca Oleracea extract (p=0.001) was significantly lower than the fatty liver control group. It seems that HIIT and Portulaca Oleracea extract can play an important role in controlling the progression of this disease by reducing the level of chemerin and insulin resistance in patients with NAFLD.

The aim of the present study was to investigate the effect of high intensity interval training (HIIT) and Portulaca Oleracea supplementation on fetuin level and insulin resistance of rat with NAFLD.

25 male Wistar rats randomly divided into 5 groups: healthy control (n = 5), fatty liver control (n = 5), supplement. (N = 5), HIIT (n = 5) and HIIT+ supplement (n = 5). To induce NAFLD, rats were fed a high-fat diet for 12 weeks. Portulaca oleracea supplement at a dose of 400 mg/kg was given to the respective groups. The HIIT training protocol was performed for 8 weeks, 5 sessions per week with 7 repetitions of 1 minute with 90% of maximum speed, which was accompanied by active rest intervals including 2 minutes of running with 20% of maximum speed.

Insulin resistance in fatty liver control group was significantly higher than healthy control group (p=0.002). Level of this index in HIIT group (p=0.01), Portulaca supplement group (P=0.037) and HIIT  group (p=0.012) were significantly lower than fatty liver control group. Also fetuin A level in liver of fatty liver control group was significantly higher than healthy control group (p=0.01). Level of this index in HIIT group (p=0.036), Portulaca supplement group (P=0.019) and HIIT combined with Portulaca supplement group (p=0.007) were significantly lower than fatty liver control group.

It seems that HIIT and Portulaca Oleracea supplementation improve insulin resistance in NAFLD by lowering hepatic fetuin A levels.

Fatty liver disease is a type of fat aggregation in the liver cells. The Portulaca oleracea plant has hypolipidemic property. The aim of this study was to evaluate efficacy of Portulaca oleracea supplementation with a combination training program on the levels of some blood factors and health indicators of obese females with non- alcoholic fatty liver disease.

40 obese women were randomly selected and divided into four groups, including training group (n=10), training + supplement group (n=10), placebo group (n=10), and supplement group (n=10). The plasma levels of cardiovascular risk factors and health factors were measured before and after the twelve week intervention. The paired samples t- test and ANOVA was used to analyze data.

Portulaca oleracea supplementation with a combination training program significantly reduced cholesterol (P=0.001), triglycerides (P<0.0001), LDL (P<0.0001), fat percentage (P<0.0001), and waist to hip ratio (P<0.0001) and a significant increase in serum level of HDL (P<0.0001), Body fat percentage (P<0.0001), waist- to- hip ratio (P=0.03), and BMI (P=0.01) in exercise + supplement group, exercise group, and supplement group (P <0.05).

Portulaca oleracea supplementation with a combination training program can be effective in reducing some blood and health indicators in obese women with non-alcoholic fatty liver