جستجوی مقالات مرتبط با کلیدواژه « پانسمان ها » در نشریات گروه « پزشکی »

Bacterial nanocellulose as a natural hydrogel with unique properties such as high biocompatibility, and non-toxicity has been investigated as a modern dressing in recent years. Accordingly, this research aimed to improve the physical and chemical properties of this biopolymer for biomedical uses by eco-printing clove plant on bacterial cellulose.

For this purpose, the purified layers of bacterial nanocellulose were printed using different amounts of clove in an eco-print method, and consequently, the properties were investigated with ATR-FTIR, XRD, FEESEM, hydrophilicity, and antibacterial activity tests.

The characterization tests confirmed the chemical nature, crystal structure and nanofibrous substrate of bacterial cellulose. Also, the eco-print process did not have a negative effect on the surface hydrophilic properties of the finished samples, and in addition, the water absorption capacity of the sample treated with 10 grams of clove plant was increased by two times compared to the untreated sample. Additionally, all the samples showed antibacterial properties against two Gram-negative (Escherichia coli) and positive (Staphylococcus aureus) bacteria, while increasing the amount of clove active substance on the samples intensified the antimicrobial properties of the layers. Accordingly, the treated samples with 10 gr of clove resulted in the formation of a 30-mm diameter inhibition zone for both bacteria mentioned above.

Based on the findings of this research, it can be concluded that the bacterial nanocellulose treated with clove plant has a high capacity as a modern environmentally friendly wound dressing.

 Diabetes is one of the main problems of health systems and a global threat to public health that has increased dramatically over the past two decades. Patients with diabetes are susceptible to multiple complications, such as diabetic foot ulcers. A diabetic foot ulcer is a common diabetes complication that has shown an increasing trend over the past decades. In treating diabetic foot ulcers, using ulcers with wound treatment is one of the critical challenges for therapists. So far, the dressing that meets all the requirements for the treatment of diabetic foot ulcers has not been produced, and the proper choice of sauce depends on the type and stage of the wound, the spread of the injury, the patient's condition, and the tissues involved.

 The present study was conducted using the one-blind clinical work method on 80 diabetic patients referred to the Alborz University of Medical Sciences supervised clinics; 40 patients with diabetic foot ulcers were treated and compared to algae, and 40 patients with alginate dressing. The information collected was analyzed using Chi-Square and T statistical tests.

There were no significant differences in gender, education level, marital condition, land disease, wound time, size, and secretion. In comparing the body mass index, there was no significant difference between the two groups in consequence of wound healing. The recovery percentage in the Alji Pad group was significantly better than in the alginate group. Also, the number of sessions for each patient in the Alji Pad group was considerably lower than in the alginate group. In reviewing the Push scoring process, we evaluated the fifth referral. Because in both groups, most people went to the fifth session. We used repeated measurement analysis. The results showed that the recovery process was good in the two groups (P <0.001), but the recovery in the Alji Pad group was significantly faster than in the alginate group.

 Algae Pad dressing in patients with diabetic foot ulcers is a simple and practical method that, according to the study of the cost of treatment, the duration of treatment is preferable to the conventional alginate dressing method.

Silver nanocrystalline dressings have recently received a great deal of attention due to their effect on various bacteria present in wound infections. The most important factor in choosing a dressing is the effect of disinfection, its effect on epithelium and its ability to control wound infection. In addition, it reduces the use of painkillers and narcotics and reduces the stress of changing the dressing by 50%. All of these solutions require optimization to achieve the best conditions with the least amount of time and cost.

In this study, the preparation of silver nanoparticles, the study of silver fabrics in terms of sterility, the design of experiments using the Taguchi method and the study of silver fabrics in terms of microbial effectiveness have been performed.     

The best state predicted by the software includes 45 grams per liter of silver nitrate, 14 grams per liter of glucose, 280 microliters of sodium hydroxide, 60 seconds mixing time and 4 hours drying time. In this case, the average diameter of the growth inhibition halo was predicted to be 4.5 cm. In the laboratory, the average diameter of the no-growth halo in this case was equal to 4.25.

Obtaining a solution for optimizing of silver nanocrystalline dressing production as well as obtaining the diameter of the non-growth halo, which indicates the more effective performance of this dressing, is of particular importance.

Patients with diabetic foot ulcers are at the risk of limb amputation. One of the most common treatments to prevent limb amputation is the use of dressings or other appropriate treatments. This study was conducted to compare the effect of two methods of vacuum-assisted closure therapy and modern dressing on wound healing in patients with diabetic foot ulcers.

This descriptive cross-sectional study (n=140) was performed on patients with grade 2 and 3 diabetic foot ulcers referring to selected hospitals affiliated with the Isfahan University of Medical Sciences, Isfahan, Iran, in 2019. The necessary data were collected using a two-part questionnaire of demographic characteristics and wound condition checklist distributed at the baseline and once a week up to 4 weeks. The Wagner ulcer classification system was used to measure the degree of the wound. Different types of new dressings, including foam, hydrocolloid, hydrogel, alginate, and hydrofilm, were used in the present study depending on the patientchr('39')s needs and wound conditions. In this study, vacuum therapy is performed by a vacuum device made in Iran. Finally, the changes in depth, discharge, shape, size, and degree of the wound were compared in the two groups. The collected data were analyzed in SPSS software (version 22) using descriptive and inferential statistics.

The results showed that the mean scores of changes in the area, discharge, depth, and degree of the wound were significant in the two groups after the intervention (P-value<0.05). It was also found that it was found that the vacuum-assisted closure therapy method was more effective in wound healing than the new dressing method.

The results indicated that both vacuum-assisted closure therapy and modern dressing methods were effective in healing diabetic foot ulcers. However, vacuum therapy-assisted closure therapy could accelerate and improve the healing process of diabetic foot ulcers, compared to the modern dressing method. Patients with diabetes, as a vulnerable group, need educational planning and counseling services regarding treatment and recovery. Since nurses are the main individuals who can provide the required services in the field of planning and caring for a patient with diabetes, they can play a key role in guiding the patient to choose the appropriate treatment for the type of wound at the onset of the treatment process.

In addition to its protective role, dressings not only prevent infection, but also accelerate wound healing process. In this study, the influence of optimizing the properties of the calendered needle-punched nonwoven fabrics using the finishing materials of Honey, Aloe Vera, Chitosan and Nano Argentum Nitrate for the end-usage as dressing has been investigated.

The prepared samples of the needle-punched nonwoven fabrics were firstly calendered and then, tested for the fundamental expected physical characteristics in the dressing purpose, i.e. crease recovery magnitude, air permeability, etc. in order to distinct initial optimized sample. In the following, the antimicrobial finishing process was carried out on the primary sample by the four studied finishing materials. The finished samples were finally analyzed simultaneously from the antimicrobial aspect and also, for the same physical properties of the dressing, as tested before, to distinguish the ultimate optimized sample. The bacteria of Staphylococcus aureus and Escherichia coli (E.coli) were also employed for antimicrobial tests.

The results demonstrated that combination of four finishing materials of Nano Silver 1%, Aloe-Vera 20%, Honey 7% and Chitosan 1% improved desired properties for wound dressing application in comparison to the other samples from one side and, showed no cellular toxicity and allergy from the other side. The FTIR’s results also implied stretching bonding of hydroxyl group in 3200-3400 wavenumber.

The needle-punched nonwoven fabric finished by the recommended antimicrobial materials can be considered as wound dressing, regarding to sufficient physical properties and hygienic condition.

Nanosilver is a nanotechnology product with antimicrobial property. It can improve efficiency, reduce cost and increase antimicrobial durability and performance of wound dressing.

This research intended to introduce a dressing that accelerated and improved the wound healing process by keeping the wound area moist and simultaneously prevented colonization by microorganisms and wound infection.

Silver nanoparticles were trapped in the pores of calcium alginate sheets, and particle loading on films took place. When this dressing is put on a wound, the silver ions are released in the wound area. After loading the silver nanoparticles; their presence in the calcium alginate structure was confirmed by FE-SEM micrographs. Wounds (2 × 2 cm2) were made on rats’ bodies and images were taken of the wound healing process on the 1st, 7th, and 14th days to study the effect of the dressing on tissues of living organisms.

Characterization of silver nanoparticles was carried out by the DLS test and Zeta potential measurement, in which the values of 61.4 nm and -20.83 mV were obtained, respectively. Antibacterial properties were studied and cell toxicity tests were performed to determine the suitable concentration. Results indicate that the optimum concentration was 100μg/l (or 17.5μg per unit area of the alginate film). Using the ImageJ software, the surface areas of the wounds were calculated, and histological studies were also conducted on wound healing. Moreover, on the 7th and 14th days, samples were taken of them to carry out histopathological investigations, and changes in skin cell shape were studied.

The results of this study suggestthat the dressing accelerates simultaneously the process of wound healing and prevents wound infection and postponement of its repair.
Conflict of interest: non declared

In spite of different tremedial methods for Totalis / Universlis Alopecia ‚ the success in hair regrowth has proved about 25 –30%. There fore, this study was performed to evaluate the efficasy of local clobetasol under occlusion. Materials

I5 cases with Totalis / Universalis Alopecia were treated by this method. The clobetasol dose was 2g daily, using a plastic cover on the scalp. The course lasted for 4 months and patients were visited monthly to evaluate the complications if any .The response was defined as regrowth of 50% terminal hair.

26.6% of cases showed improvemet. Recurrence was seen in only 1 patient, so the success rate was 20% after a 6 month follow-up. The complciations included transient folliculitis in only one case was observed.

It seems that local clobetasol under occlusion is effective in curing Totalis / Universalis Alopecia.