جستجوی مقالات مرتبط با کلیدواژه « ABO Blood Group » در نشریات گروه « پزشکی »
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Aims
Urinary tract infection is the most common adult bacterial infection worldwide. Antigens of ABO and Lewis blood groups may influence bacterial adherence and lead to an increase in the frequency of urinary tract infections in adults. This study aimed to evaluate the relationship of ABO and Lewis blood groups with urinary tract infections.
Materials & MethodsIn this experimental study, a blood sample of 80 urinary tract infection patients from AL-Sader Teaching Hospital, Iraq, and 50 healthy persons was used for the determination of ABO and Lewis blood groups by agglutination assay. Urine samples of urinary tract infection patients were cultured and identified based on culture characteristics, gram staining, and biochemical tests.
FindingsUrinary tract infection was significantly higher in patients with the O blood group (42.5%) and the Lewis (a-b-) phenotype (38.8%) than in patients with other blood groups and the control group. Escherichia coli was the most common bacterial isolate observed in urinary tract infection patients. Also, E. coli was significantly higher in the UTI patients with the O blood group and the Lewis (a-b-) phenotype.
ConclusionPeople of the O blood group and the Lewis (a-b-) phenotype are more susceptible to urinary tract infections. Escherichia coli is the main cause of urinary tract infections.
Keywords: Urinary Tract Infection, Escherichia Coli, ABO Blood Group, Lewis Blood Group, Secretor Status} -
Background
Colorectal cancer (CC) is one of the most important causes of death due to cancer in the world. The association of blood groups with CC in many races has been reported in previous studies. So far, no study has evaluated the relationship between blood group type, tumor location, and polyp type.
ObjectivesThis study aimed at evaluating the association of the ABO blood group and CC, tumor location, and polyp type.
MethodsIn this case-control study, 802 subjects (401 cases and 401 controls), who underwent surgery at our medical centers between 2014 and 2021, were included. The case group was selected from the hospital records of patients with CC, and the controls were selected from non-cancer patients who were admitted to the same centers for reasons other than cancer. Patients’ demographic characteristics and clinical and pathology findings were extracted from the medical profile, and blood group information was extracted from the blood bank. Multivariate logistic regression analysis was used for the predictive variables of CC.
ResultsThe risk of CC in patients with blood type A was significantly higher than non-A. While the risk of developing CC in patients with blood type O was significantly lower than non-O O. The risk of developing neoplastic polyps was significantly higher in patients with blood type A compared to non-A. The results of multivariate analysis showed that ABO blood type A (OR Adju: 1.66) and O (OR Adju: 0.78) and neoplastic polyp type (OR Adju: 1.36) were associated with CC.
ConclusionsThe results of this study showed that ABO blood group type was significantly related to CC and polyp type.
Keywords: ABO Blood Group, Colorectal Cancer, Intestinal Polyps} -
مقدمه
بین گروه های خونی ABO و افزایش حساسیت به بیماری های خاص از جمله حوادث قلبی عروقی، عفونت های ویروسی و باکتریایی، سرطان کولورکتال، آنوریسم داخل جمجمه و بیماری های ترومبوآمبولی، ارتباط قوی وجود دارد. مطالعه حاضر با هدف بررسی ارتباط بین گروه های خونی مادر و عوارض نامطلوب بارداری انجام گرفت.
روش کار:
در این مطالعه مقطعی (توصیفی - تحلیلی) و گذشته نگر، پرونده 400 نفر از بیمارانی که در سال 98-1396 جهت زایمان به بیمارستان علی ابن ابی طالب زاهدان مراجعه کردند، وارد مطالعه شدند. متغیرهای این مطالعه شامل: گروه های خونی ABO، پره اکلامپسی، اکلامپسی، دکولمان، دیابت حاملگی، زایمان زودرس و محدودیت رشد داخل رحمی بود. ابزار جمع آوری داده ها شامل فرم اطلاعاتی بود که اطلاعات مورد نیاز وارد آنها شد. تجزیه و تحلیل داده ها با استفاده از نرم افزار آماری SPSS (نسخه 22) و آزمون کای دو انجام شد. میزان p کمتر از 05/0 معنی دار در نظر گرفته شد.
یافته هااز مجموع 400 زن باردار با میانگین سنی 53/7±09/33 سال، 153 نفر (3/38%) دارای گروه خونی O، 116 نفر (0/29%) B، 97 نفر (3/24%) A و 34 نفر (5/8%) AB بود. بین گروه های خونی ABO و پره اکلامپسی (848/0=p)، دکولمان (833/0=p)، زایمان زودرس (705/0=p) و محدودیت رشد داخل رحمی (214/0=p) ارتباط آماری معنی داری وجود نداشت، ولی دیابت حاملگی (049/0=p) و اکلامپسی (039/0=p) با گروه های خونی ارتباط معنی داری داشتند.
نتیجه گیریبین پره اکلامپسی، دکولمان، زایمان زودرس و محدودیت رشد داخل رحمی با گروه های خونی ABO اختلاف معنی داری وجود نداشت، اما بین اکلامپسی و دیابت حاملگی با گروه های خونی ABO اختلاف معنی داری وجود داشت.
کلید واژگان: گروه خونی ABO, پره اکلامپسی, اکلامپسی, دکولمان, دیابت حاملگی, زایمان زودرس و محدودیت رشد جنینی}IntroductionThere is a strong association between ABO blood groups and increased susceptibility to certain diseases including cardiovascular events, viral and bacterial infections, colorectal cancer, intracranial aneurysms and thromboembolic diseases. The present study was performed aimed to investigate the relationship between maternal blood groups and adverse pregnancy complications.
MethodsIn this cross-sectional (descriptive-analytical) and retrospective study, the file of 400 pregnant women referred to the maternity hospital of Ali Ebn Abi Taleb Hospital of Zahedan from 2017 to 2019 were included. The variables of this study were ABO blood groups, preeclampsia, eclampsia, placental abruption, gestational diabetes mellitus, preterm labor and intrauterine growth restriction. The data collection tool included an information form in which the required information was entered. Data were analyzed by SPSS (version 22) and chi-square test. P<0.05 was considered statistically significant.
ResultsOut of a total of 400 pregnant women with a mean age of 33.09±7.53 years, 153 (38.3%) had blood type O, 116 (29%) B, 97 (24.3%) A and 34 (8.5%) AB. The relationship between ABO blood groups and preeclampsia (p = 0.848), placental abruption (p = 0.833), preterm birth (p = 0.705) and intrauterine growth restriction (p = 0.214) was not statistically significant, but gestational diabetes (p=0.049) and eclampsia (p=0.039) had a significant relationship with blood groups.
ConclusionThere was no significant difference between preeclampsia, placental abruption, preterm labor and intrauterine growth restriction with ABO blood groups, but there was a significant difference between eclampsia and gestational diabetes with ABO blood groups.
Keywords: ABO blood group, Eclampsia, Fetal Growth Retardation, Gestational diabetes, Placenta Abruption, Preeclampsia, Preterm delivery} -
Background
The rapid spread of the virus around the world is raising alarms among scientists to identify vulnerable people who are at greater risk of infection. In this regard, the present study aimed to determine the prevalence of severe acute respiratory syndrome coronavirus 2 in different blood groups.
MethodsTo find relevant studies, a comprehensive and systematic search was conducted based on the PRISMA guidelines in international databases such as PubMed, Scopus, Web of Sciences, and Google Scholar by December 31, 2020.
ResultsAfter the audit and exclusion of double and unrelated studies, 19 articles were included in the analysis. The most prevalent blood types in alive patients were A and O which calculated the aggregate prevalence at - 39.06 (95% CI: 36.22-41.94) and 35.60 (95% CI: 32.48-38.79). In addition, patients with blood groups B and AB were less than two other groups. The aggregated/estimated prevalence was 7.72 (95% CI: 5.06-10.88) and 16.23 (95% CI: 12.86-19.91) for AB and B, respectively. The results for the deceased had a similar pattern that was high for blood types A and O.
ConclusionsThe current meta-analysis validated different prevalence rates of blood group types in patients with COVID-19, confirming that types A and O blood groups are the most prevalent types of deaths and live patients.
Keywords: COVID-19, ABO blood group, Alive, Dead, Meta-analysis} -
Background
Systemic lupus erythematous (SLE) and rheumatoid arthritis (RA) are autoimmune diseases in which the antigen-antibody system plays an important role. As blood group and Rh are determined by the presence or absence of antigens on the surface of red blood cells (RBCs), we aimed to determine the distribution of ABO and Rh blood groups in SLE and RA patients and its association with disease manifestations.
MethodsThis short communication is based on a study that was conducted on 434 SLE and 828 RA patients. We evaluated the distribution of ABO and Rh blood groups in RA and SLE patients.
ResultsThis study projected that in lupus patients, Coombs-positive autoimmune hemolytic anemia and arthritis were more common among the B blood type and Rh-positive group, respectively. Furthermore, there was no relation between ABO and Rh blood group and rheumatoid factor (RF) and anti-Cyclic Citrullinated Peptide (anti-CCP) seropositivity. Moreover, there was no difference in distribution of blood groups in RA and SLE patients.
ConclusionThe higher frequency of blood group B in hemolytic anemia, and positive Rh in arthritis in lupus patients, develop the hypothesis of probable role of ABO blood group antigen in some manifestations of lupus.
Keywords: Rheumatoid Arthritis, Systemic Lupus Erythematosus, ABO blood group, Rh blood group} -
بررسی ارتباط میان گروه های خونی ABO و بیماری عروق کرونری در بیماران تحت آنژیوگرافی الکتیو عروق کرونرپیش زمینه و هدف
آنتی ژن های گروه خونی ABO در مطالعات مختلفی نشان داده شده اند که با بیماری عروق کرونر و مرگ و میر قلبی عروقی مرتبط می باشند. اما نتایج متناقضی در این زمینه نیز وجود دارند. ما بر آن شدیم تا ارتباط میان های گروه خونی ABO و شدت درگیری بیماری عروق کرونر را در بیمارانی که تحت آنژیوگرافی الکتیو تشخیصی قرار میگیرند، تعیین نماییم.
مواد و روش هادر یک مطالعه گذشته نگر، بیمارانی که تحت آنژیوگرافی الکتیو تشخیصی قرار میگیرند در طی سال 2019 وارد مطالعه خواهند شد. تشخیص بیماری عروق کرونر براساس تنگی لومن عروق کرونری <50% بصورت خفیف، 50 تا 70% بصورت متوسط، و >70% بصورت شدید تعریف گردید. همچنین تعداد عروق کرونری درگیر نیز تعیین گردید. نوع گروه خونی ABO و نوع Rh نیز تعیین شدند.
یافته هاتعداد 192 بیمار که تحت آنژیوگرافی الکتیو تشخیصی قرار گرفتند، بررسی شدند. میانگین سنی بیماران 59.6 ± 10.7 سال و تعداد 113 نفر (9/58%) از بیماران مرد بودند. بعد از تقسیم بیماران به دو دسته بیماران دارای گروه خونی O و گروه خونی non-O، تعداد عروق کرونری درگیر و شدت تنگی لومن عروق کرونر در بین دو گروه متفاوت نبود. این یافته ها در بین بیمارانی که دارای گروه های خونی A, B, AB, and O بودند نیز قابل مقایسه بود. بدون در نظر گرفتن گروه خونی، بیماران دارای Rh منفی دارای شیوع بالاتری از تنگی عروق کرونری 50-70% در مقایسه با بیماران دارای Rh مثبت بودند (p=0.043).
نتیجه گیریاین مطالعه نشان داد که ارتباطی میان گروه خونی ABO و شدت بیماری عروق کرونر در بین بیمارانی که تحت آنژیوگرافی الکتیو تشخیصی قرار گرفتند، وجود ندارد. همچنین، Rh منفی با شدت درگیری کمترعروق کرونری در مقایسه با Rh مثبت همراهی داشت.
کلید واژگان: گروه خونی ABO, آنتی ژن رزوس, بیماری عروق کرونر, آنژیوگرافی عروق کرونر}Background & AimsThe ABO blood group antigens have been associated with coronary artery disease (CAD) and cardiovascular mortality. However, there are some controversies in this regard. We sought to determine the association between the ABO blood group and the severity of CAD among patients undergoing elective diagnostic coronary angiography (CAG).
Materials & MethodsIn this retrospective study, patients undergoing elective CAG were recruited during a year, from January to December 2019. The diagnosis of CAD was based on the narrowing of coronary artery lumen (<50% as mild CAD, 50-70% as moderate CAD, and >70% as severe CAD). Subsequently, the number of involved coronary arteries was also defined. The ABO blood group and Rh status were also identified.
ResultsA total of 192 patients undergoing elective CAG were assessed. The patients’ mean age was 59.6 ± 10.7 years, and 113 (58.9%) subjects were male. After categorization into the O and the non-O blood groups, the number of involved coronary arteries and the severity of lumen narrowing were not significantly different between groups. Those values were also comparable between the A, B, AB, and O blood groups. Irrespective of blood group, patients with negative Rh had a higher prevalence of coronary artery narrowing (50-70%) compared to patients with positive Rh (p=0.043).
ConclusionThis study showed no association between the ABO blood group and the severity of CAD among patients undergoing elective CAG. Moreover, negative Rh was associated with the lower degrees of coronary artery narrowing compared to positive Rh.
Keywords: ABO blood group, Rhesus antigen, coronary artery disease, coronary angiography} -
Introduction
There is paucity of data about the possible role of ABO antigen in response to pharmacologic reperfusion therapy in ST-segment elevation myocardial infarction (STEMI) and its relationship with ST segment recovery; thus, we aimed to evaluate the association of ABO antigen with ST-segment resolution in STEMI patients treated with thrombolysis.
MethodsThis prospective and observational study was conducted between March 2016 and September 2017 on patients with first acute STEMI within the first 12 hours after onset of symptoms treated with thrombolysis. Myocardial reperfusion success was determined by single-lead ST-segment recovery in 12-lead ECG. Patients were considered as responders if ST-segment resolved ≥50% or were assigned as non-responders if ST-segment resolution was <50%. Univariable and multivariable analyses were performed to examine the contribution of “A” and “B” blood group antigens to ST-segment resolution and the occurrence of major adverse cardiovascular or cerebrovascular event (MACCE). Odds ratio (OR) with 95% confidence interval (CI) were reported for each variable.
ResultsIn this study 303 patients (187 males and 116 females) with a mean age of 56.6 ± 16.8 (ranging from 39 to 87 years) were enrolled. 184 patients (60.7%) were responders and 119 patients (39.2%) were non-responders. The presence of either A (4.5 folds increase) or B (5.4 folds increase) antigen was associated with a higher likelihood of a response to thrombolytic therapy, while had not effect on the occurrence of MACCE.
ConclusionWe conclude that the presence of A or B blood group antigens is associated with a better response to thrombolytic therapy in patients with acute STEMI. This finding may imply a higher likelihood for thrombotic occlusion of coronary arteries in patients who have either A or B antigen in their blood.
Keywords: ABO Blood Group, Acute Myocardial Infarction, ST-Segment Resolution, Thrombus Burden, Thrombolysis} -
Introduction
Several studies have found that certain diseases are associated with ABO blood groups. The aim of the present study was to investigate the correlation of ABO Rh blood group with dental malocclusion in the population of Mysuru.
Materials and MethodsIn this study patients of 15–28 years of age will be selected, irrespective of gender from the hospital, Mysuru. It is an observational study with a duration of 3–4months. A total of 278 subjects between the age group of 15-28 years who visited the JSS hospital, Mysuru were recruited for this study. The maxillary and mandibular molar relation of teeth in maximum intercuspation using Angle’s classification were recorded. Blood group was evaluated using the ABO blood grouping system. Mean, Standard deviation, frequency, percentage were used for descriptive statistics. Chi-square test was used for inferential statistics. Statistical Package of Social Science (SPSS), version 16 was used for statistical
analysis.ResultsOut of 278 people ‘O’ blood group was found to be most commonly associated with Angle’s Class I malocclusion (71.3%). Class II div I and div II was found to be more common in ‘A’ blood group (42.68%) and (4.9%) respectively. Class III being most common in ‘B’ blood group (6.5%).
ConclusionsA significant correlation exists between blood group and malocclusion. The prevalence of malocclusions being highest in blood group O, followed by A, B and AB in Mysuru. Class II div I malocclusion was more prevalent in ‘A’ followed by ‘B’ blood group.
Keywords: ABO blood group, correlation, malocclusion, Mysuru population, Rh factor} -
سابقه و هدفتعیین عوامل خطر بیماری های قلبی برای، غربالگری و پیشگیری از بیماری ضروری است. در این مطالعه ارتباط بین گروه های خونی ABO و خطر ابتلا به بیماری های قلبی و عروقی مورد بررسی قرار گرفت.مواد و روش هادر این مطالعه مقطعی توصیفی – تحلیلی، 1353 نفر از افراد 60 سال و بالاتر شهر امیرکلا مورد بررسی قرار گرفتند. تشخیص بیماری قلبی – عروقی بر اساس سابقه پزشکی، لیست داروهای مصرفی و مستندات درمانی فرد صورت گرفت و فنوتیپ گروه های خونی ABO مورد سنجش قرار گرفت و در نهایت فراوانی بیماری های کاردیوواسکولار در چهار گروه خونی مختلف با استفاده از نرم افزار آماری SPSS16 مورد مقایسه قرار گرفت.یافته هامیانگین سنی نمونه ها 30/7±21/69 سال و شامل 754 مرد (7/55 درصد) و 599 زن (3/44 درصد) بودند. در این مطالعه، بیش ترین فراوانی گروه های خونی O (5/33 درصد) و گروه خونی B (33 درصد) بود. آنژین صدری با گروه خونی A ارتباط معناداری را نشان داد (039/0=p)؛ ولی سکته مغزی (624/0=(p، سکته قلبی (229/0=(p، نارسایی قلبی (866/0=(p، هیپرتانسیون (623/0=(p و هم چنین سایر عوامل خطر با گروه های خونی ABO ارتباط نداشتند.
استنتاج: بر اساس نتایج به دست آمده، به جز ارتباط بین گروه خونی A و آنژین صدری، در سایر موارد بین فنوتایپ های گروه خونی ABO و ریسک ابتلا به بیماری های قلبی-عروقی ارتباط معناداری وجود ندارد.کلید واژگان: عوامل خطر, بیماری قلبی, عروقی, گروه های خونی ABO}Background andPurposeIdentifying potential risk factors for cardiovascular diseases is essential for screening and disease prevention. In this study, the association between ABO blood groups and risk of cardiovascular diseases was assessed.Materials And MethodsIn a cross-sectional research, 1353 consecutive elderly in Amirkola, north of Iran enrolled. Cardiovascular disease was determined according to medical history, any medications, and other medical documents. Also, the ABO blood group was determined. Finally, the frequency of cardiovascular disease was compared between ABO blood groups. Data analysis was done in SPSS 16.ResultsThe mean age of the population studied was 69.21±7.30 years and 754 (55.7%) and 599 (44.3%) were males and females, respectively. Blood group O (33.5%) and B (33%) phenotypes were common types in this population. Angina pectoris was significantly associated with A blood group (P=0.039). But no relationship was found between ABO blood group and cerebral stroke (P=0.624), myocardial infarction (P =0.229), heart failure (P =0.866), hypertension (P =0.623), and other risk factors.ConclusionAccording to the our findings, a relationship was only detected between A blood group phenotype and angina pectoris, while no any significant association was detected between ABO blood groups and risk of other cardiovascular diseases.Keywords: ABO blood group, risk, cardiovascular disease} -
زمینه و اهدافعفونت هلیکوباکتر پیلوری در حال حاضر به صورت یک مسئله بهداشتی جهان گستر تبدیل شده است. این عفونت می تواند باعث بیماری های مختلف گوارشی شود. نقش گروه های خونی در نحوه پاسخگویی بدن به میکروارگانیسم ها و گسترش اختلالات دستگاه گوارش تثبیت شده است. هدف از این مطالعه بررسی ارتباط بین گروه های خونی و سن و جنس در جمعیت ایرانی با شدت آلودگی به این باکتری است.مواد و روش کاردر این مطالعه 160 بیمار دارای ناراحتی های گوارشی که به بیمارستان هاجر مراجعه کرده بودند وارد مطالعه شدند. نمونه های بیوپسی بیماران ازلحاظ آلوده بودن به هلیکوباکتر پیلوری با روش PCR برای ژن های 16SRNA و glmM بررسی شدند و تعیین گروه های خونی بیماران نیز با تست روتین هماگلوتیناسیون صورت گرفت.
یافته ها ونتیجه گیریمشاهده شد که 61/87% از بیماران ازلحاظ وجود باکتری مثبت بودند و 61 نفر از بیماران منفی بودند. در میان بیماران آلوده به باکتری 62/26% زن بودند. بیشترین فراوانی گروه های خونی ABO در میان بیماران آلوده برای گروه خونی O با 40/66% بود (p > 0.05). 12/77% از افراد Rh مثبت نیز آلوده به هلیکوباکتر پیلوری بودند (P< 0.05). ارتباط معنی داری بین سن و جنس با میزان آلودگی مشاهده نشد. شدت آلودگی به این باکتری نیز در بیماران دارای گروه خونی O+ بیشتر از بقیه مشاهده شد (P<0.05). مثبت بودن Rh در بیماران آلوده و گروه خونی O ممکن است در تشدید آلودگی به این باکتری نقش داشته باشد.کلید واژگان: هلیکوباکتر پیلوری, گروه خونی ABO, فاکتور رزوس, PCR}Background And AimsHelicobacter pylori infection currently become as an endemic worldwide health issue. The infection causes variety of gastrointestinal diseases. The role of blood groups is established in bodys response to microorganisms and the development of gastrointestinal disorders. This study aimed to investigate the relationship between blood groups, age and gender of Iranian population and the severity of infection with this bacteria.Materials And MethodsThe study included 160 patients with dyspepsia symptoms referred to Hajar hospital in Shahrekord. Biopsy specimens were investigated in terms of being infected with H. pylori by using PCR for 16SRNA gene and glmM gene and blood groups of patients were determined by using hemagglutination routine test.
Results andConclusionsIt was observed that 61.87% of patients were positive in terms of bacteria existence and 61 of them were negative. 62.26% of infected patients with bacteria were female. The highest frequency of ABO blood groups among infected patients, belongs to O blood group with 40.66 percent (P>0.05). H. pylori was found in 77.12% of Rh patients (P 0.05). The severity of this bacterial disease were observed in patients with blood group O more than others (PKeywords: Helicobacter pylori, ABO blood group, Rhesus factor, PCR} -
زمینههلیکوباکتر پیلوری یکی از شایع ترین باکتری های عفونت زا، عامل ایجاد بیماری هایی نظیر گاستریت مزمن، زخم معده، آدنوکارسینوما و غیره می باشد. مطالعات اپیدمیولوژیکی نشان داده اند که افراد با گروه خونی O بیشتر در معرض ابتلا به این عفونت می باشند. هدف از مطالعه حاضر بررسی ارتباط بین شیوع عفونت هلیکوباکتر پیلوری با گروه های خونی ABO و Rh در بین دانشجویان نظامی و سربازان وظیفه در شهر تهران می باشد.مواد و روش هادر این مطالعه توصیفی تعداد 417 نفر با سن 27-18 سال وارد مطالعه شدند و این افراد از بین دانشجویان دانشگاه علوم پزشکی ارتش، دانشگاه افسری امام علی (ع) و سربازان وظیفه انتخاب شدند. اطلاعات فردی، اجتماعی و بهداشی افراد نیز از طریق پرسشنامه جمع آوری گردید. فنوتایپ گروه های خونی ABO و Rh تمام افراد مورد مطالعه توسط آزمایش هماگلوتیناسیون استاندارد تعیین گردید. سطوح آنتی بادی Anti- H.pylori IgG در سرم تمام افراد مورد مطالعه توسط تست ELISA تعیین گردید. داده های به دست آمده، توسط نرم افزار SPSS ویرایش 16 و آزمون Chi-square مورد تجزیه و تحلیل قرار گرفتند.یافته هادر مجموع 183 نفر (9/43 درصد) از 417 نفر مورد مطالعه، از لحاظ سرمی مثبت و تعداد 234 (1/56 درصد) منفی بودند. شیوع عفونت در دانشجویان دانشگاه علوم پزشکی ارتش در مقایسه با دو گروه دیگر کاهش معنی داری را نشان داد. همچنین شیوع عفونت، در گروه های با جمعیت خانوادگی بیش از پنج نفر افزایش معنی داری نسبت به گروه های با جمعیت کمتر نشان داد.نتیجه گیریهیچ گونه ارتباطی بین گروه های خونی ABO و Rh با عفونت هلیکوباکتر پیلوری در مطالعه حاضر مشاهده نگردید.کلید واژگان: هلیکوباکتر پیلوری, گروه خونی ABO, گروه خونی Rh, دانشجویان نظامی}BackgroundHelicobacter pylori (H. Pylori) is one of the most common infectious bacteria cause diseases such as chronic gastritis, peptic ulcer, adenocarcinoma, etc. Epidemiological studies have demonstrated that individuals who had O blood group were more likely to develop peptic ulcers. The aim of present study was to investigate the association between the prevalence of H. Pylori infection in soldiers and military students with ABO, Rh blood group in Tehran city.Materials And MethodsIn this descriptive study 417 individuals aged 18-27 years who were selected among military students of AJAUMS (Aja University of Medical Sciences) University of Afsari Imam Ali and soldiers. Personal, social and health information of individuals were collected through questionnaires. Phenotype of ABO blood groups and Rh in all participants were studied by a standard hemagglutination test. Antibody levels of Anti- H. pylori IgG in serum of all participants were determined by ELISA test. Collected data analyzed by using SPSSsoftware version 16 and Chi-square test.ResultsOverall 183 (43.9%) of 417 subjects were seropositive, and 234 (56.1%) subjects were seronegative. Prevalence of infection in AJAUMS students compared to other two groups showed a significant decrease. However, the prevalence of infection in the group of persons with more than five family members was significantly higher than the group with less than 5.ConclusionThere was no association between ABO, Rh blood groups with H. Pylori infection.Keywords: Helicobacter Pylori, ABO blood group, Rh blood group, military students}
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Background and Objectives
Lichen planus (LP) is a skin disease with unknown origin; however, some studies revealed that ABO blood group is correlated with LP; the current study aimed at evaluating this possible relationship.
MethodsThe current case-control study was conducted on 79 patients with LP referring to Shohada-e-Tajrish and Loghman-e-Hakim hospitals as well as 79 healthy donors as the control group.
ResultsThe most common type of LP was cutaneous phenotype (57 out of 79); in the patients group, the frequency of ABO blood groups was A (38%), O (36.7%), B (16.5%) and AB (8.9%), while it was O (34.2%), A (27.8%), B (26.6%), and AB (11.4%) in the control group. Blood group A observed more frequently in patients with mucosal phenotype (P = 0.012), but the correlation between LP and Rh was not significant (P = 0.3).
ConclusionsThe results of the current study revealed that Rh has no impacts on LP. Based on the current study findings, individuals with blood group A were more susceptible to mucosal phenotype of LP
Keywords: Rh, Lichen Planus, ABO Blood Group, Skin Disease} -
Urology Journal, Volume:13 Issue: 4, Jul-Aug 2016, PP 2765 -2772PurposeIn this study, we evaluated the prognostic significance of the ABO blood type in patients with renal cell carcinoma (RCC) who had undergone partial or radical nephrectomy.Materials And MethodsInformation on the ABO blood type was obtained from 1750 patients with RCC. A total of 1243 men and 507 women (mean age, 55.41 ± 12.43 years) with RCC who had undergone partial or radical nephrectomy were enrolled in this study. The median follow-up duration was 35.0 months (interquartile range [IQR], 16.0-67.0). During the follow-up period, 271 patients experienced RCC recurrence, and 137 patients died from RCC.ResultsType A was the most common blood type (568, 32.5%), followed by type O (525, 30.0%), type B (464, 26.5%), and type AB (193, 11.0%). Generally, blood type was not associated with any clinicopathological factors. Unlike blood type O, the multivariate analysis of progression-free survival (PFS) showed that blood type non-O (A, B, and AB) was an independent prognostic factor for a worse outcome (95% confidence interval [CI]: 1.24- 2.37, hazard ratio [HR] = 1.71, P = .001; 95% CI: 1.08-2.13, HR = 1.51, P = .016; 95% CI: 1.03-2.43, HR = 1.58, P = .037, respectively). Cancer-specific survival (CSS) analysis showed that blood type A was an independent factor associated with a worse prognosis for CSS (95% CI: 1.05-2.64, HR 1.66, P = .031, respectively).ConclusionThe ABO blood type is significantly associated with PFS and CSS in patients with RCC following partial or radical nephrectomy. Blood type non-O (A, B, and AB) is an independent prognostic factor for a worse PFS outcome, and blood type A is an independent factor associated with a worse CSS prognosis.Keywords: ABO blood group, Renal Cell Carcinoma, Prognosis, Prognostic Factor, Nephrectomy}
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BackgroundThe ABO blood group antigens play a role in the pathophysiology of some diseases and several researches have investigated this relationship in the field of dermatology. In the present study, an attempt was made to find the distribution of blood types in patients with pemphigus vulgaris and chronic plaque type psoriasis.MethodFifty patients with chronic plaque type psoriasis, 50 patients with pemphigus vulgaris and 100 healthy persons as control group, were selected as the study population. ABO blood grouping was determined by the cell type tube test method, using standard commercial anti/A, anti/B and 5% suspension of red blood cells. Chi square test was used to compare the frequency of ABO blood groups in patients and control groups.ResultAmong the 50 patients with psoriasis, 21 (42%) had blood group O, 15 (30%) blood group A, 10 (20%) blood group B and 8 (4%) had blood group AB. Among the 50 patients in the pemphigus group, 22 (44%) had blood group O, 19 (38%) blood group A, 8 (16%) blood group B and 1 (2%) had blood group AB. The distribution of blood groups in patients with these two diseases was not significantly different from the control group.ConclusionDespite some researches, which found associations between blood group antigens and psoriasis or pemphigus, this study did not find any such relationship.Keywords: ABO blood group, psoriasis, pemphigus vulgaris, skin disease}
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Background And AimsThe ABO blood group system is recognized as major and clinically significant blood group. This group is not only important in terms of blood transfusion and organ transplantation, but also has been utilized in genetic, fertility and infertility researches. The objective of the present study was to evaluate a possible relationship between ABO blood group system and ASA with male infertility.Materials And MethodsThis is a retrospective, case-control study. Our study was carried out on samples referred to Research and Clinical Center for Infertility, Yazd, Iran. ABO blood group, titer of ASA and sperm analysis data of 150 infertile males (case group) and 150 fertile males (control group) was evaluated based on medical records of the patients. Data were then analyzed with SPSS 16 software using t-test and chi-square tests.ResultsOur results indicated that there is a significant relationship between male infertility and O blood group (p= 0.02) whereas no significant relationship was observed between O blood group and fertility in the control group (p= 0.08). In both groups the amount of ASA agglutination was statistically significant (p= 0.001) whereas no significant relationship was detected between blood group and ASA in infertile males (p= 0.18).ConclusionThe present study revealed that there is a significant relationship between blood group O and male infertility as well as sperm agglutination and thus the concentration of ASA in infertile males is higher than of fertile males thereby demanding appropriate intervention strategies.Keywords: ABO blood group, Anti, sperm antibody, Male infertility}
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زمینه و هدفترومبوآمبولی وریدی یکی از سه علت قلبی- عروقی مرگ و میر و آمبولی ریه شایع ترین علت قابل پیشگیری مرگ در میان افراد بستری در بیمارستان می باشد. با توجه به شیوع بالا، اهمیت مطالعات اتیولو ژیک بیماری ها و وجودگزارش های مختلفی مبنی بر نقش گروه های خونی ABO در بروز بیماری ها واز جمله ترومبوآمبولی وریدی، این پژوهش به منظور بررسی گروه های خونی ABO در بیماران بستری مبتلا به ترومبوآمبولی وریدی انجام گرفت.روش کاردراین مطالعه توصیفی - مقطعی، 200 بیمار که با تشخیص قطعی ترومبوز وریدی عمقی و آمبولی ریه در طی سال 1390 در بیمارستان های امام خمینی، فاطمی و علوی شهر اردبیل بستری بودند، مورد مطالعه قرارگرفتند. تشخیص قطعی بیماری بر اساس سونوگرافی کالرداپلر و سی تی آنژیوگرافی ریه انجام گرفت. گروه خونی بیماران و عوامل خطر بیماری ثبت گردید. اطلاعات بدست امده، همراه با گزارش های اپیدمیولوژیک موجود در رابطه با گروه های خونی جامعه اردبیل و ایران با استفاده از نرم افزار SPSS و آزمون های آماری تست t وکای دو مورد تجزیه و تحلیل قرارگرفت.یافته هااز بین 200 بیمار مبتلا به ترومبوآمبولی وریدی، 140 نفر (70%) مبتلا به DVT و 60 نفر (30%) مبتلا به PE بودند. 92 نفر از بیماران (46%) مرد و 108 نفر (54%) زن بودند. میانگین سنی بیماران 19 ± 52 سال بود. شایعترین گروه خونی، از نوع گروه خونی A به میزان 5/47% بود و از نظر آماری ارتباطی میان نوع بیماری (DVT یا PE) و گروه خونی وجود نداشت (55/0 = p).
فراوانی گروه های خونی (A OR:2/914) و (B OR: 1/608) در بیماران مبتلا به VTE نسبت به جامعه اردبیل و ایران بیشتر بوده ولی در گروه خونی (O OR: 0/632)، درصد کمتری نسبت به افراد هم گروه خود در جامعه را تشکیل می دادند، که این اختلاف از لحاظ آماری معنی دار بود (05/0 > p). فراوانی گروه خونی AB در هر 3 گروه (مطالعه انجام شده، اردبیل و ایران) مشابه بود.نتیجه گیریارتباط گروه های خونی ABO با ترومبوآمبولی وریدی که در مطالعات متعددی بررسی شده، برای اولین بار در ایران و در بیمارستان های اردبیل مورد بررسی قرار گرفته است و به نظر می رسد که بین گروه خونی A و B با بروز VTE ارتباط وجود داشته باشد. مطالعات تحقیقی بیشتری برای بررسی این رابطه لازم است.
کلید واژگان: ترومبوآمبولی وریدی, ترومبوز وریدی عمقی, آمبولی ریه, گروه خونی ABO}Background and ObjectivesVenous thromboembolism (VTE) is one of the three causes of mortality made by cardiovascular disease and pulmonary embolism is the most common preventable causes of mortality among hospitalized patients. Considering high prevalence, the importance of etiologic studies of diseases and different previous reports regarding the role of blood groups on occurrence of diseases such as VTE, this study was carried out to determine the blood groups of the hospitalized patients with diagnosis of VTE.MethodsThis cross-sectional study was carried out on 200 hospitalized patients with the diagnosis of deep vein thrombosis (DVT) and pulmonary embolism (PE) in Imam, Fatemi and Alavi hospitals in Ardebil. The final diagnosis was made by c olour D oppler ultrasound and pulmonary CT angiography and blood groups and risk factors were determined. Results of this study analysed along with the previous epidemiologic reports related with blood groups in Ardebil and Iran population using chi-square and t-test and SPSS software.ResultsOf 200 patients with VTE, 140 patients were affected with DVT and 60 patients with PE. In this study, 92 patients were males and 108 were females. The mean age of patients was 52 ± 19 years. The most prevalent blood group was type A with a rate of 47.5%. There was no correlation between the diseases namely DVT or PE and blood groups (P=0.55). Frequency of type A (OR: 2.914) and B (OR: 1.608) in patients with VTE was more than Ardebil and Iran population but the type O (OR: 0.632) was less than those population. These differences were statistically significant. The frequency of type AB was similar in all groups.ConclusionThe Correlation between blood groups and venous thromboembolism, which have been discussed in many studies, have been investigated in Iran and at medical centres of Ardebil University of Medical Science for first time. It seems the type of blood groups (A and B) is effective in frequency of VTE. More studies are needed on the correlation between blood groups and VTE.Keywords: ABO Blood Group, Deep Vein Thrombosis, Pulmonary Embolism, Venous Thromboembolism} -
Acute lymphoblastic leukemia (ALL) constitute a family of genetically heterogeneous lymphoid neoplasms derived from B- and T-lymphoid progenitors. ALL affects both children and adults. Diagnosis is based on morphologic, immunophenotypic, and genetic features that allow differentiation from normal progenitors and other hematopoietic and nonhematopoietic neoplasms. The aim of this study was to investigate the association between ALL and ABO blood group.Material And MethodThis is a case-control study that was carried out in Amir Oncology Hospital in Shiraz during 2011 to2013. The case group consisted of 293 patients with acute lymphoblastic leukemia. And compared with 300 subject in control group (the age in the case group was between 2-5 year, and the age in the control group was between 2-45 year). Statistical analyzes was done performed by chi –square test. The results was considered significant when p value <0.05. (CI:0.95)ResultsThe ABO blood group distribution was 82(A), 59 (B), 24 (AB) and 128(O) in patient with Acute Lymphoblastic Leukemia and the blood group of 300 participants in the control group include, 63% (25) A, 69% (25.6) B, 18 % 06.8) AB and 101% (42.6) O. The ABO blood group distribution showed that there is significant differences between ABO blood group and patients with acute lymphoblastic leukemia.ConclusionThis study showed significant association between ALL and ABO blood group and showed that blood group AB was associated with a higher risk of All (p value<0.001).Keywords: Acute lymphoblastic leukemia, ABO blood group, Children}
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Observational Cross Sectional Study on Blood DonorsInternational Journal of Medical Toxicology and Forensic Medicine, Volume:1 Issue: 2, Autumn 2011, PP 65 -69BackgroundThis study was conducted to document the frequency ABO & rhesus blood groups in potential male blood donor belong to south area of Karnataka.MethodsThe data of blood donors from July 2009 to December 2009.ResultsTotal number of donors studied was 3048. The commonest blood group was O present in 37.87% followed by B in 29.98%, A in 23.88% and AB in 8.29%. While 95.41% donors were Rh positive and 4.59% was Rh negative. The maximum donors were between in age group 20-39 years. The maximum prevalence of Hemoglobin % ranges from 13.0-13.9 about 2983(75.11%). The maximum prevalence of weight among the donors was between 60 to 69Kgs about 1201(39.40%) and the least weight appears between 80 to 90Kgs about 254(8.4%).ConclusionBlood group O is the commonest ABO blood group and 95.41% are Rh + in this area, the maximum prevalence of donors in age group, Hb% and Weight are 20.39 yrs, 13.0-13.5 gm% and 50-69 Kgs respectively.Keywords: ABO blood group, Rhesus blood group, Prevalence of age group, weight, Hb% in blood donors}
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Although ABO incompatibility between mother and fetus has long been suspected as cause of spontaneous abortion in man, its precise contribution has not been completely resolved. In spite of reports in which the incompatible mating was recognized to be a cause of habitual abortion, and which eventually results in infertility or a reduction in the number of living children compared with the number in compatible matings, such effects were not observed in other studies. The aim of this review article was to show some evidence of relationship between ABO incompatibility and spontaneous abortion.Keywords: spontaneous abortion, ABO blood group, incompatibility}
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BackgroundEarly Childhood Caries (ECC) is defined as a specific pattern of dental caries in infants and toddlers that may lead to diverse and serious oral consequences as well as an overall detriment to general health.ObjectivesThe purpose of this study was to evaluate the association between the mode of mother's delivery and ECC in their children.Patients andMethodsThe study was conducted as a longitudinal study using 120 mothers and their neonates up to two years of age in Kerman, Iran. Sample selection was according to a pilot study and a sample size formula. The women were examined at the ninth month of pregnancy and their babies were examined on the first day of life, and then every six months on a regular basis by only one examiner. The data was written on checklist and was analyzed by SPSS (version 18) and by Chi-square as well as Sign test.ResultsAnalysis of the data demonstrated a statistically significant relationship between gender and occurrence of ECC, but no statistically significant relationship between mode of delivery and occurrence of ECC, as well as ABO blood groups and occurrence of ECC were seen.ConclusionsThere is not any significant association between mode of delivery and occurrence of ECC, despite the positive association between occurrence of ECC and genderKeywords: ABO Blood Group, Dental Caries, Gender, Kerman}
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