جستجوی مقالات مرتبط با کلیدواژه « Attention deficit disorder with hyperactivity » در نشریات گروه « پزشکی »

 Roughly 10% of children aged 3 -17 in the USA are diagnosed with attention-deficit hyperactivity disorder (ADHD), and minorities are less likely to initiate common pharmacologic treatment. We conducted a review of the literature to examine meditation as a safe, effective, and low-cost alternative.

 We searched PubMed and other journals using “meditation,” “mindfulness,” “minority,” related keywords, and relevant MeSH terms. Eligible studies involved racial/ethnic minorities in the USA, reported quantitative psychosocial outcomes, and were published in a peer-reviewed, English-language journal.

 Out of 119 “hits,” 111 were eliminated as duplicates or were not relevant. A full-text review of the remaining eight revealed that none fully met our eligibility criteria. Besides the obvious lack of studies, those reviewed reported incomplete demographic and clinical data. They also employed different and inconsistent research methodologies, interventions and modalities, and statistical analyses. This hindered understanding exactly which populations may benefit from meditation, and for which specific symptoms.

 We recommend a socio-ecological model in examining intervention modalities, especially in the context of intrapersonal, interpersonal, organizational, environmental, and policy domains. We also suggest the possible inclusion of research older than 10 years, conducted outside of the USA, on minority and non-minority populations, for supplementary and confirmatory data. We advocate for consistency in study design and data collection, which would help align research conducted in different countries. Searches should also include variations of meditation such as “mindfulness” and “guided imagery,” and associated symptoms and comorbidities of ADHD, including “learning disorder” and “behavioral problems.”

Sluggish cognitive tempo (SCT) is an essential psychological and psychiatric construct affecting distinct aspects of a person’s life. This study investigates whether SCT affects the quality of life (QoL) and whether this effect will persist after controlling attention deficit hyperactivity disorder (ADHD) symptoms, depression, and anxiety.

This descriptive correlational study was conducted on college students in Mashhad City, Iran. The participants were 279 students selected by the convenience sampling method from September 2020 to February 2021. The data collection tools included the Barkley adult ADHD rating scale-IV (Barkley, 2011), the depression, anxiety, and stress scale (Lovibond & Lovibond, 1995), and the 36-item short-form health survey (SF-36) (Ware & Sherbourne, 1992). Hierarchical regression analysis was used to examine the hypotheses. Data analysis was performed using the SPSS software, version 24. The significance level of the research was considered α=0.05.

Correlation results showed that SCT, ADHD symptoms, anxiety, and depression are negatively correlated with the physical and mental dimensions of QoL. The results of the hierarchical regression analysis showed that SCT was negatively associated with the total QoL (F change=4.1, P<0.05) and mental dimensions of QoL (F change=3.8, P<0.05) after controlling anxiety, depression, and ADHD symptoms.

SCT is associated with low QoL among Iranian college students, and this relationship remains present after controlling ADHD, anxiety, and depression. In addition, the results of this research emphasize the importance of considering QoL in prospective research and SCT intervention.

Micronutrient interventions for Adult Attention-Deficit/Hyperactivity (ADHD) could be helpful. We used a naturally processed whole wheat grains supplement containing higher doses of micronutrients named Nutrition Bio Shield (NBS). We aimed to determine its effects on ADHD symptoms in adults. 

Fifty-two medication-free adults with ADHD were randomly assigned to receive 5 g of NBS supplement or placebo daily for eight weeks. 

Twenty-three participants in the NBS group and 24 participants in the placebo group completed the study. After 8 weeks, compared with the placebo, the ADHD scores significantly decreased (mean difference 95%CI): -4.9 (-8.6 to -1.1); p=0.01; Cohen’s d=0.74), and quality of life significantly improved (mean difference 95%CI): 5.6 (0.12 to 11.3); p=0.04; Cohen’s d=0.59) in the NBS group. The observed side effects were minimal and did not differ statistically between groups. 

Quality of life increased during consumption of the NBS supplement, compared to the placebo. However, despite the statistically significant findings, these changes in ADHD symptoms were small and the clinical significance may be low (about 5%).

This research investigates the alleles of Variable Number of Tandem Repeats (VNTR) intron 8 of the gene SLC6A3 with attention-deficit / hyperactivity disorder (ADHD) in children and adolescents.

The study’s target population consisted of children and adolescents referred to the specialized clinic, as well as students attending school in Rasht city during 2021-2022. A sample of 95 children between the ages of 6 and 10 with ADHD was selected as the ADHD group, and 95 healthy children were selected as the control group using purposive sampling. The subjects completed the Child Symptom Inventory-4 (CSI-4) checklist after a clinical interview, and demographic information was collected. Genetic sampling was carried out through hair follicles. The sequence of interest was proliferated using the Polymerase Chain Reaction technique )PCR(; afterward, the samples were used for genotype identification on polyacrylamide gel electrophoresis.

The chi-square test results indicated that the 5R / 5R genotype (P = 0.026, χ2 = 7.26) and the 5R allele (P = 0.002, χ2 = 9.35) had a higher frequency compared to the control group. Additionally, the odds ratio test indicated that, compared to other genotypes and alleles, the 5R / 5R genotype (OR = 2.75, 95% CI = 1.29-5.82, P = 0.01) and the 5R allele (OR = 2.02, 95% CI = 1.28-3.19, P = 0.002) increase the odds of developing ADHD by 2.7 and 2 times higher, respectively.

The present study successfully showed the association between intron 8 gene polymorphism, which is responsible for encoding the dopamine transporter as well as ADHD in children and adolescents in Iran.

In current study, we aimed to investigate if Attention Deficit Hyperactivity Disorder (ADHD) is better to be categorized among behavioral or neurodevelopmental disorders, based on some familial and environmental factors. 

We conducted correlation analysis to identify psychiatric disorders in the dataset which have an important impact on ADHD. Also, we used machine learning-based approaches combined with a feature selection algorithm to cluster and classify ADHD as a behavioral or neurodevelopmental disorder.

Model evaluation showed that ADHD is clustered in the group of behavioral disorders with the accuracy of 78%. Furthermore, Support Vector Machine (SVM) classified ADHD as a behavioral disorder with the accuracy of 72.66% and as a neurodevelopmental disorder with the accuracy of 60.07%.

In sum, we can say that our findings support categorizations systems like HiTOP in comparison to DSM-5. However, as biological factors were not included in our analysis, it should be considered with caution and examined in future researches.

A systematic review and meta-analysis was conducted to determine the association between exposure to maternal diabetes and ADHD in the offspring. Major electronic databases, including Web of Science, PubMed, Scopus, Embase, and Proquest, were searched from inception until December 2018. The New Castle-Ottawa scale was used to assess the quality of the included studies. A fixed effects model was applied for analysis. Seven studies including a total of 5,658,871 individuals were retained. A significant association was found between maternal diabetes and ADHD [OR=1.23, 95% CI: 1.117, 1.345]. There was a significant heterogeneity (I^2=77.7, P<0.0001), while Egger’s and Begg’s test were not significant. This study showed a significant relationship between maternal diabetes and ADHD; however, more well-designed studies are needed to confirm the results.

Numerous researchers have examined the effect of diet on Attention Deficit Hyperactivity Disorder (ADHD). The purpose of this study is to compare the symptoms of ADHD in children fed horse milk versus conventionally fed cow's milk. Thirty patients aged 6 to 14 with ADHD were randomly selected and divided into two groups in this randomized double-blind crossover study. All patients completed a 45-day period of consuming 250 mL horse or cow milk, as well as continued Ritalin (1 mg/kg) treatment. The wash out period was considered one week. Symptoms are recorded using the Conners rating scale (CS). The CS of the parents decreased significantly (P value≤0.001) in the group that first received horse milk, but increased (P value=0.007) after consuming cow's milk. After consumption of horse milk, the parent's CS was significantly different from that of cow milk (P value= 0.001). Teachers' CS decreased significantly following horse milk consumption (P=0.001) and increased significantly following cow milk consumption (P=0.028) in this group. The average teacher's CS after cow milk differed significantly from that after horse milk (P value= 0.024). The CS of the parents did not change significantly (P value=0.913) in the group that first consumed cow's milk. However, it was significantly decreased (P value=0.004) after receiving horse milk. The CS of the teachers in this group did not change after the cow's milk (P value=0.282). However, following the administration of horse milk, the mean of CS decreased significantly (P=0.003). The average of the teacher's CS after consuming cow milk differed significantly from that of horse milk (P value= 0.010). In both groups, there was no significant difference in the mean of parents and teachers CS before and after the washout period (P>0.05). According to the study, horse milk consumption was significantly more effective than cow milk at lowering scores.

Meier-Gorlin syndrome (MGS) is a rare autosomal recessive disorder with homozygous or heterozygous mutations in one of the five following genes (ORC1, ORC4, ORC6, CDT1, and CDC6). This syndrome is characterized by the triad of short stature (pre/postnatal), microtia, and patella hypoplasia/aplasia. Special features included microcephaly, microstomia, full lips, micrognathia, narrow convex, and high nasal bridge nose. Also, it may be accompanied by feeding problems, skeletal disorders, urogenital or respiratory anomalies, and intelligence disorders. This case report describes the first Persian MGS accompanied by neonatal seizure, mental retardation, and attention deficit hyperactivity disorder.

Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder. Various factors can delay the timely diagnosis of adult ADHD. The brown attention deficit disorder scales (BADDS) is a consistent measure of attention deficit disorder (ADD) across the life span.

This article aims to examine the reliability and validity of a Persian version of the BADDS.

A total of 100 participants were enrolled in this descriptive study by convenience sampling. Cases were recruited from the adult ADHD outpatient clinic of Roozbeh psychiatry hospital in 2019. Controls were from the caregivers of patients presenting to Roozbeh general psychiatry outpatient clinic. The conners' adult ADHD rating scale was used to measure concurrent validity.

Cronbach's Alpha was 0.979 for the test, ranging from 0.888 to 0.942 for the clusters. Also, the intra-class coefficient (0.977) confirmed strong internal stability. For the cut-off point of 55, the sensitivity was 96%, and the specificity was 74%. Our study demonstrated a significant relationship between the C scale and the D scale of the Conners' test and the total score of the BADDS questionnaire (r = 0.61 and r = 0.64, respectively), verifying the concurrent validity of the instrument. Construct validity was evaluated by the t-test. All five clusters' total and subtotal scores were significantly higher in the patients compared to the controls.

The Persian version of BADDS is reliable and valid and can be used in clinical settings.

Attention deficit hyperactivity disorder (ADHD) is a considerably common childhood‑onset neurodevelopmental disorder, often associated with socio‑behavioral and academic difficulties. There is an increased risk for development of a range of future problems such as psychiatric disorders, difficulties in employment, and relationships. The aim of this study was to know the prevalence and determinants of ADHD among primary school children in district Dehradun and to assess the learning difficulties and classroom behavior in these students.

In this cross‑sectional study, overall, 228 students (aged 6–12 years) studying in a primary school were assessed for ADHD after seeking the written informed consent from their parents. The data were analyzed using Excel sheet and SPSS software (22.0 version). For all qualitative measures, frequency and percentages were calculated, and for quantitative measures, mean and standard deviation were calculated. For analysis of categorical values, Chi‑square test was used. P < 0.05 was considered statistically significant.

The prevalence of ADHD was found to be 11.8% based on the teacher tool only and 1.75% based on the parent and teacher tools combined. ADHD was found to be significantly more in males. Inattention was the most prevalent subtype of ADHD, and children screened positive for ADHD had significant learning difficulties at various levels.

The possibility of ADHD in students with academic difficulties should not be ignored as children with ADHD usually face significant problems at school such as learning difficulties and have been shown to be at increased risk for a broad range of negative outcomes. Early identification and treatment of ADHD can significantly reduce the rates of some of these poor outcomes. Screening these children in the early years will help the parents, children, teachers, and community at large.