جستجوی مقالات مرتبط با کلیدواژه « Gastrectomy » در نشریات گروه « پزشکی »

Previous studies have reported that gastrectomy and fundectomy can induce osteopenia. Body fat index is a new index of obesity that shows central obesity and other risks of obesity. Sleeve gastrectomy (SG) is a bariatric surgery and a new technique introduced as subsleeve, which only resected fundus of the stomach. In this study, it has been shown the effect of subsleeve and SG on fat index and bone densitometry in an animal model.

Rabbits were underlined SG, fundectomy (surgical removal of fundus), or sham‑operated (controls without any resection), and after 12 weeks, fat index and bone densitometry were obtained.

Our study showed that there was no significant difference between SG and fundectomy groups in bone mass density and fat mass after surgery in comparison with presurgery condition. SG group were associated with lower fat index and bone density, and it showed significantly decrease in weight after 1.5 months.

Sub‑SG did not show any significant effect on fat index and bone densitometry in comparison with SG. However, we found lower fat index in sleeve group of rabbits, but it was not statistically significant.

This is a novel observation report on patients undergoing spine surgery with a history of bariatric procedures. Acknowledgment of aggregated complications in such patients can prevent catastrophic outcomes.

We report three patients with spinal disorders and a history of bariatric surgery who developed pulmonary embolism following spine surgery. None of the patients had a history of venous thromboembolism or deep vein thrombosis (DVT) before this event. All patients were given thromboprophylaxis after both bariatric and spine surgery, including intra-and post-operative mechanical and pharmacological thromboprophylaxis upon discharge.

Patients undergoing spine surgery with a history of bariatric procedures are at increased risk of developing venous thromboembolic complications, including pulmonary embolism. We recommend extensive venous thromboembolic evaluation and treating these patients as high-risk individuals even in the absence of active thromboembolic disease.

To investigate whether there is a relationship between tumour location and prognostic factors in gastric cancer.

Total 293 patients who underwent curative surgical resection for gastric cancer were retrospective analysed. Siewert Type II and III tumours were defined as PGC. More distally located tumours were defined as DGC. Siewert Type I tumours were excluded.

Of the 293 patients, 78 were diagnosed with PGC and 215 had DGC. There was a significant relationship between preoperative/postoperative chemotherapy administration, gastrectomy type, presence of lymphatic metastasis, TNM stage and tumour localization (p < 0.05). There was no significant difference between PGC and DGC in terms of length of hospital stay (p = 0.137). Five-year survival rates for PGC and DGC were 48.4% and 45.8%, respectively (p = 0.863). pT stage, preoperative and postoperative chemotherapy were determined as independent risk factors (p < 0.05). The location of the tumour and the type of surgical resection did not affect the prognosis (p > 0.05).

Tumour localization is not a prognostic factor in gastric cancer. When safe surgical margins were provided in DGC, total gastrectomy for DGC did not affect survival.

The prognostic significance of an SRC histology in gastric cancer is still a matter of debate. There have been only limited studies of SRC gastriccancer based on the new definition.

The current research was targeted toward investigating the incidence of signet ring cell (SRC) histology in patients with gastric cancer and its prognostic significance for disease staging.

Thisretrospective research was performed on 309 patients at the Kartal Koşuyolu High Specialization Training and Research Hospital Gastroenterology Surgery Clinic in Turkey, between November 2006 and September 2019. For the purpose of the study, the clinicopathological features and survival status of the patients were examined in the presence of SRC histology.

According to the results, 71.4% of the patients had gastric cancer with non-SRC histology, and the rest (28.6%) had SRC histology. The presence of SRC histology was found to be correlated with young age (P=0.007), advanced depth of wall invasion (P=0.001), number of positive lymph nodes (P=0.022), and presence of vascular invasion (P=0.044). In addition, SRC histology presence was found to be in association with a good prognosis of stage I gastric cancer (P=0.045) but a poor prognosis of stage III disease (P=0.034). However, the results revealed no significant association between stage II gastric cancer and overall survival.

Our findings were indicative of the association of survival with good prognosis of stage I and poor prognosis of stage III among patients with gastric cancer and SRC histology. However, no prognostic significance could be established for overall survival.

Eating disorders (EDs) are widely known by abnormal eating behaviors associated with significant medical complications. Bulimia nervosa (BN) is an eating disorder characterized by uncontrolled episodes of overeating typically followed by some form of compensatory behaviors. We aimed to determine the relationships between socio-demographic characteristics, biochemical markers, and cytokine levels in BN candidates for laparoscopic sleeve gastrectomy (LSG).

A case-control study was designed among 76 BN participants of Iranian descent who were candidates for LSG based on defined criteria for Bulimia by Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). The healthy control subjects (n = 42) were selected at random from academic staff in the college. Moreover, levels of biochemical parameters and serum cytokines were measured in serum samples.

Routine consumption of caffeine (odds ratio [OR] = 3.1, 95% CI: 1.23–6.41, P = 0.013), tobacco (OR = 1.8, 95% CI: 0.67–3.57, P = 0.03), and alcohol (OR = 3.6, 95% CI: 0.84–7.18, P = 0.048), and depression history (OR = 2.8, 95% CI: 0.76– 5.79, P = 0.037) were substantially more common among patients with bulimia. Also, the serum levels of fasting blood sugar (P < 0.001), HbA1c (P = 0.04), cholesterol (P = 0.03), triglycerides (P = 0.01), blood urea nitrogen (P = 0.03), and pro-inflammatory cytokines including IL-1β, IL-6, and TNF-α were significantly higher in BN candidates for LSG (P ≤ 0.001).

Our findings reveal that lifestyle-related risk factors and a depression history were both related with a significantly increased risk of BN among the candidates for LSG. Furthermore, there is a relationship between clinical characteristics as well as levels of various biochemical and cytokines parameters in serum of BN patients.

The rising prevalence of obesity in today populations has led obese individuals to seek medical interventions. Aside from special diets, routine exercise and in some cases, medical treatment, most of the obese patients, favoring those with morbid or super obesity can benefit from bariatric surgery to lose weight. Laparoscopic sleeve gastrectomy (LSG) is relatively new method to limit the compliance of stomach. The consequent quick satiety during each meal results in gradual weight loss in patients. We investigated the efficacy and safety of this method among a group of our patients.

This cross‑sectional study was conducted in Isfahan, Iran, from January 2012 to January 2013. Thirty‑five cases of obesity that had undergone LSG were enrolled and their baseline data of weight, body mass index (BMI), blood sugar, lipid profile, liver function indexes and blood pressure were collected. The patients were followed up for 6 months. The 6‑month results were analyzed.

There was significant reduction in BMI, weight, blood sugar, blood pressure, liver enzymes and lipid profile components(P < 0.05), except for alkaline phosphatase (ALP) (P = 0.3). The average of excess weight loss percentage after 6 months was 69.2 ± 20.9%. No mortality occurred. Two of the patients had micro anastomotic leaks that were treated with nonoperative management. Acase of gross leakage was treated with tube jejunostomy.

Our study confirmed the efficacy and safety of LSG as a single surgical intervention for body weight reduction in morbidly and super obese patients.