جستجوی مقالات مرتبط با کلیدواژه « High-intensity Interval Swimming » در نشریات گروه « پزشکی »

The molecular mechanisms of the improvement of exercise on memory are in the aura of ambiguity.Therefore, the aim of this research was studying the effect of eight weeks of high-intensity intermittent swimming training (HIIST) on the biochemical factors of lipid metabolism and hippocampal memory function of male rats with non-alcoholic steatohepatitis (NASH).

The present study was experimental. 40 male Sprague-Dawley rats were divided into two groups: healthy (n=20) and high-fat HFD (n=20) groups. Rats in the HFD group were fed a high-fat diet for eight weeks with the aim of inducing NASH. After proving the disease in HFD group rats, the remaining rats were randomly divided into four groups: healthy-sedentary (n=9), healthy-swimming (n=9), sedentary disease (n=9) and diseased-swimming (n=9). The exercise groups performed eight weeks of HIIST (three sessions/week, each session lasting 30 minutes). At the end, FNDC5 protein was evaluated by western blot method and brain hippocampal irisin and serum FFA by ELISA method. Memory performance was measured by the water Maz-Morris behavioral test. One-way ANOVA test was used to determine the difference between groups, and Bonferroni's post hoc test was used to determine the difference between two groups (p<0.05).

The findings showed that there was a significant difference in the FNDC5 protein and irisin of the brain hippocampus and serum FFA and in memory function variables between the groups (p<0.05).

HIIST in NASH model can activate lipid metabolism in the hippocampus of the brain and improve memory function. However, more research is needed in this field.

Accumulation of fat in the liver tissue is known as the most important cause of non-alcoholic steatohepatitis, which is associated with a decrease in the protein of hepatic peroxisome proliferator-activated receptors (PPAR-α). This study aimed to investigate the effect of eight weeks of high-intensity interval training (HIST) on PPAR-α and liver enzymes in high-fat diet-induced non-alcoholic steatohepatitis rats.

The current research was semi-experimental. 40 Spraguedauli male rats (age: 6 to 8 weeks and weight: 230 ± 20 grams) were selected and divided into two equal groups, healthy and high-fat diet (HFD). The HFD group was subjected to gavage for eight weeks with the aim of inducing the disease. Rats were divided into four groups: control-healthy (n=9), healthy-swimming (n=9), control- disease (n=9) and disease -swimming (n=9). The training groups performed HIST for eight weeks (three sessions per week, each session lasting 30 minutes). In the end, liver PPAR-α was measured by western blot analysis; and ALT, AST and GGT enzymes in serum level were measured by photometric method. One-way analysis of variance and Bonferroni's post hoc test were used to analyze the data. Significant level (P≥0.05) and all statistical methods were performed using SPSS16 software.

HIST controlled the weight gain caused by HFD and there was a significant decrease in serum ALT and AST in the healthy-swimming and sick-swimming groups compared to the control-patient group and a significant decrease in serum GGT in the healthy-swimming group compared to the control-patient (P≤0.001) and patient-swimming (P≤0.044) were observed. A significant increase in hepatic PPAR-α was observed in healthy-swimming patients compared to the control-patients (P≤0.002).

HIST can control body weight and reduce liver enzymes. However, more research is needed to obtain definitive results.

The aim of the present study was to investigated the comparison effects of eight weeks of continuous and high intensity interval swimming on irisin tissue levels and insulin sensitivity in male rats with metabolic syndrome.

48 male Wistar rats with six weeks of age and a weight range of 150-180 gr were randomly divided into four groups of eight including: standard control, metabolic syndrome control, moderate continuous swimming+metabolic syndrome (CT+MetS) and high-intensity interval swimming+metabolic syndrome (HIIT+MetS). The training was carriedout for eight weeks and five days a week, equivalent to 65 and almost 100 percent of the maximum oxygen consumption, respectively, for the program of CT and HIIT swimming. Measurement of blood and tissue variables (visceral fat and liver) was done by ELISA method and statistical analysis was done using one-way analysis of variance and at a significance level of p<0.05.

The results showed that CT and HIIT swimming after induction of metabolic syndrome increased level of irisin in the liver tissue and visceral fat of rats (p=0.002 and p=0.0001, respectively); so the changes were higher after HIIT. The glucose levels in the CT and HIIT swimming group were significantly lower than the standard and the metabolic syndrome control (p=0.0001) groups. No significant difference was observed in the insulin sensitivity (p=0.67) between the training groups and the metabolic syndrome control group.

It is possible that moderate and high intensity intermittent swimming induce protective effects on metabolic syndrome by increasing irisin and reducing blood glucose.

Omentin-1 and chemerin are adipocytes that are inversely associated with obesity. The purpose of the present study was to compare the effect of eight weeks of Submaximal and High
Intensity Interval swimming practice on changes in serum levels of omentin-1 and chemerin in overweight young men. in this semi-experimental study among statistical population (110 students), 24 male students (22.5±1.67 years) purposefully with overweight (26.93±0.69)  were divided into two sub-maximal swimming groups (60-67% of maximum heart rate) and High-intensity training swings (80-90% of maximal heart rate).The training protocol included 8 weeks and 3 days per week and each session with 45-60 minutes. It turned out before and 24 hours after exercise, blood 5cc was taken from the subjects. T-test was used to examine the differences between the groups and for inter-group differences, independent T-test with a significance level of p<0.05 was used.  Both submaximal swimming training (p=0.001) and high intensity interval (p=0.01) resulted in an increase in the levels of omentin-1 and the serum chemerin level in both submaximal swimming (p=0.005) and high intensity interval (p=0.02) increased significantly. These results were associated with weight loss, body mass index, waist-hip ratio, fat percentage and aerobic capacity increase in both groups (p<0.05). Therefore, it can be said that eight weeks of submaximal swimming and high intensity interval, lead to an increase in serum levels of omentin-1 and a decrease in chemerin and obesity-related factors.