جستجوی مقالات مرتبط با کلیدواژه « Solid-State » در نشریات گروه « پزشکی »

 This study assessed the effects of two remineralizing agents namely MI Paste Plus containing casein phosphopeptide amorphous calcium phosphate fluoride (CPP-ACFP) and Remin Pro containing hydroxyapatite, fluoride and xylitol (HFX) with/without erbium-doped yttrium aluminium garnet (Er:YAG) and CO2 laser irradiation on demineralized enamel microhardness.

In this in vitro study, 70 sound human premolars were mesiodistally sectioned, demineralized at a pH of 4.6 for 8 hours, and randomly divided into 7 remineralization groups (n=10): of (I) MI Paste Plus (CPP-ACFP), (II) Remin Pro (HFX), (III) MI Paste Plus+CO2 laser (0.7 W power, 50 Hz), (IV) Remin Pro+CO2 laser, (V) MI Paste Plus+Er:YAG laser (1 W power, 10 Hz), (VI) Remin Pro+Er:YAG laser, and (VII) negative control. The Vickers hardness number of specimens was then measured. The groups were compared by one-way ANOVA and Tukey’s test (α=0.05).

The mean microhardness was 319.8±49.9, 325.3±44.6, 359.4±35.7, 296.4±33.7, 319.9±58.1, 358.9±28.4, and 240.0±41.6 kg/mm2 in groups 1 to 7, respectively. The difference in microhardness was significant among the groups (P<0.0001). Pairwise comparisons revealed significant differences in microhardness between all groups (P≤0.03) except between groups 1 and 2, 1 and 5, 2 and 5, and 3 and 6 (P>0.05).

Both Remin Pro (containing HFX) and MI Paste Plus (containing CPP-ACFP) can cause enamel remineralization.  MI Paste Plus+CO2 laser irradiation and Remin Pro+Er:YAG laser irradiation were significantly more effective than the application of each remineralizing agent alone.

Porcelain chipping and delamination are among the shortcomings of all-ceramic restorations. This study aimed to assess the effect of laser irradiation and sandblasting on shear bond strength (SBS) of zirconia to veneering porcelain.

In this in vitro, experimental study, 60 zirconia blocks were randomly divided into three groups (n=20) for surface treatment with Er:YAG laser, sandblasting, and no surface treatment (control). Each group was randomly divided into two subgroups (n=10) for porcelain application by the layering or the pressing technique. The surface roughness, SBS, and failure mode were determined and analyzed using two-way ANOVA, Tukey’s HSD test, Chi-square test, and Pearson’s correlation test (alpha=0.05).

The mean SBS was 8.16±3.66 MPa, 9.32±2.7 MPa, and 11.85±3.06 MPa in the control, laser, and sandblasting groups, respectively. The SBS was significantly different among the three groups (P=0.002). The failure mode of the three groups was not significantly different (P>0.05). The sandblasted group showed significantly higher surface roughness than the control and laser groups (P<0.001).

Sandblasting yielded higher SBS particularly when the porcelain was applied by the layering technique. Although laser irradiation increased the SBS, the difference with the control group was not statistically significant.

Providing a reliable attachment between the bracket base and zirconia surface is a prerequisite for exertion of orthodontic forces. The purpose of the present study was to evaluate the effect of two surface treatment methods and three primers on shear bond strength (SBS) of orthodontic brackets to zirconia surface.

 Zirconia blocks were milled and embedded in acrylic resin. The polished zirconia surfaces were randomly prepared with sandblasting (SB) and Er:YAG laser application (LA). Each group of 45 (SB and LA) was further divided into 3 subgroups of 15.  The subgroups received different primers namely Z-Prime Plus, MKZ primer and Clearfil SE Bond Primer. The SBS values were measured and compared using two-way ANOVA. SPSS 21 for Macintosh was used for all statistical analyses. Level of significance was set at P<0.05.

 The SB group exhibited a mean SBS of 14.393 MPa, which was significantly higher than the mean SBS recorded for LA group (5.683 MPa; P<0.05). In SB subgroups, there was no significant difference among the primers in SBS (P= 0.391), but this was not the case for laser subgroups (P< 0.05) and the subgroups that received Clearfil SE and Z-Prime Plus had higher SBS than the MKZ primer subgroup.

 This study suggests that simultaneous use of sandblasting and primers containing 10-methacryloyloxydecyl dihydrogen phosphate (MDP) monomer can result in acceptable SBS of brackets to zirconia surfaces.

The aim of this study was to assess the shear bond strength (SBS) of zirconia ceramic to composite resin with various surface treatments following pressure changes.

Totally, 135 zirconia blocks were prepared by computer-aided design/computer-aided manufacturing technology. The samples were divided into 9 groups (n=15). Three surface treatments including sandblasting, tribo-chemical preparation, and laser application were used. For each method, 45 samples were considered and tested under different pressure conditions. Z-Prime Plus primer was used for bonding of all samples to composite cylinders. All specimens were stored in water for 24 h, underwent thermocycling, and were then placed in a pressure chamber under normal-, high-, and low-pressure conditions. Then, the SBS test was performed for each sample. Data were analyzed by two-way and one-way ANOVA (α=0.05).

The SBS was significantly higher in sandblasting and tribochemical preparation compared with laser irradiation (P<0.05). There was no statistically significant difference in SBS of sandblasting and tribochemical preparation methods (P>0.05). Sandblasting, tribochemical preparation, and laser methods did not show a significant difference in SBS at different pressures (P>0.05).

Sandblasting and tribochemical preparation yielded a higher SBS than laser. Different pressures had no effect on SBS, irrespective of surface preparation method.

Due to the complications of root canal treatment, conservative modalities to preserve pulp vitality are favorable. Direct pulp capping (DPC) refers to the coverage of the pulp tissue exposed by a biocompatible agent that can improve the prognosis of the tooth by 44% to 95%. Some recent studies have reported more predictable results (a success rate of about 90%) for DPC with laser and regenerative materials such as mineral trioxide aggregate (MTA). This study aimed to clinically compare DPC with ProRoot MTA alone and in combination with Er:YAG (erbium-doped yttrium aluminium garnet) laser irradiation (2940 nm).

This clinical trial was conducted on 26 patients with a mean age of 29 years (in the range of 17 to 46 years) who required DPC following pulp exposure during deep caries removal. The teeth were divided into two groups. In the control group, the teeth underwent DPC with ProRoot MTA while in the test group, the teeth were first irradiated with a 2940 nm Er:YAG laser and then underwent DPC with ProRoot MTA. The patients were recalled at one, 3 and 6 months for the follow-up (clinical and radiographic examinations). The data were analyzed using Fisher exact test.

The success rate was 75% in the laser group and 93% in the control group. The groups were not significantly different (P>0.05).

No significant difference was found in terms of the success rate of DPC with ProRoot MTA alone and in combination with Er:YAG laser irradiation.

The conventional procedure for removal of porcelain laminate veneers (PLVs) is time-consuming and inconvenient. The purpose of this study was to evaluate the efficacy of Er:YAG laser for debonding of PLVs.

Forty-eight intact extracted human maxillary anterior teeth received discoid PLVs (24 feldspathic and 24 e-max ceramic). The PLVs had 0.7 mm thickness and 4 mm diameter. After cementation of all PLVs with a light-cure cement, samples were stored at 37ºC distilled water for 48 h. Samples of each ceramic were randomly divided into 3 groups of 8 samples. Then, laser was irra-diated on the cemented PLVs as follows: (I) feldspathic PLVs without laser irradiation (control group), (II) feldspathic PLVs with laser irradiation (6 s, 10 Hz, 200 mJ, 2 W), (III) feldspathic PLVs with laser irradiation (6 s, 10 Hz, 300 mJ, 3 W), (IV) e-max PLVs without laser irradiation (control group), (V) e-max PLVs with laser radiation (6 s, 10 Hz, 200 mJ, 2 W), (VI) e-max PLVs with laser irradiation (6 s, 10 Hz, 300 mJ, 3 W). The shear bond strength of all samples was measured using a universal testing machine. We used Mann-Whitney and Kruskal-Wallis tests for data analysis (P<0.05).

Laser irradiation decreased the shear bond strength of both ceramics. But this decrease was only significant for the e-max group (P<0.05). No significant difference was found between different laser irradiation powers in the two ceramic groups.

Er: YAG laser is effective for debonding of e-max PLVs.

In this study a solid dispersion and a physical mixture of cilazapril (CIL) with a biopolymer - polyvinylpyrrolidone (PVP) as a carrier were prepared so as to investigate the effect of PVP on the stability of CIL. CIL is unstable in solid state and decomposes rapidly under humid conditions. It requires stabilization to ensure safety of its use. The studied CIL/PVP formulations were prepared by milling and evaporation technique. Their identity was confirmed by FT-IR method. The stability of CIL in the CIL/PVP formulations was assessed by forced ageing test under isothermic conditions using RP-HPLC. The influence of temperature (experimental conditions: RH 76.4% and T = 70, 75, 80, 85, and 90 oC) and the effect of relative humidity (experimental conditions: RH 25.0%, 50.9%, 60.9%, 66.5%, 76.4%, T = 90 °C) on the rate of CIL degradation were examined. It was established that the process of CIL decay in the studied forms followed first-order kinetics with the formation of one degradation product - cilazaprilat. The degradation rate constant of this reaction was lower than that for pure CIL. The energy of activation of the CIL degradation in the presence of PVP was higher than that of pure CIL. Furthermore, CIL incorporated into PVP exhibited lower sensitivity to moisture. Based on these data PVP was considered as a potential stabilizing substance for CIL-containing dosage forms.

Successful root treatment depends on elimination of microorganisms from the root canal. Considering incomplete removal of bacteria from the canal by usual methods, lasers have been suggested as a new modality. Despite their anti-bacterial properties, lasers can cause thermal changes. This study assessed the thermal changes of root surface in pulpectomy of primary teeth following the use of Er:YAG laser.
Sixty primary anterior teeth were collected and prepared by K-file up to number 50. Then, they were randomly divided into two groups and were irradiated with Er:YAG laser. The first group was irradiated with 1 W laser and the second group with 1.5 W laser. The laser irradiation time was two 10-second cycles with a 2-second interval in both groups. Thermal changes were measured by a thermometer in the apical and coronal areas per second. The results were analyzed by repeated measures ANOVA considering the laser power as between-subject variable.
There was a temperature increase in the coronal and apical areas in use of 1 W power. There was a temperature rise in the coronal and apical areas in use of 1.5 W power. The temperature rise in the apical third was more than that in the coronal third; also, the average temperature rise was more in use of 1.5 W power than 1 W power.
As the average temperature increase was not more than 7°C in any group, this type of laser seems to be suitable for root treatment of primary anterior teeth.

The purpose of this in vitro study was to evaluate the microleakage of cervical cavities prepared by Er:YAG laser or high-speed hand piece and bur.
This in vitro experimental study was performed on 40 sound permanent third molar teeth randomly assigned into two equal groups (n=20). In the first group, high-speed hand piece and bur and in the second group Er:YAG laser was used to prepare class V cavities on the buccal or lingual surfaces. Filtek Z250 composite resin was used as the restorative material. The teeth were thermocycled for 1000 cycles, placed in 2% methylene blue solution for 24 hours, sectioned at the center of restoration and evaluated under a stereomicroscope at x40 magnification for microleakage. Data were analyzed using Mann-Whitney U test at 0.05 level of significance.
There was no significant difference between the occlusal or gingival margin microleakage of cavities prepared with Er:YAG laser and high-speed hand piece (P=0.445 and P=0.758, respectively). However, the difference in the occlusal and gingival margins was significant within the high-speed hand piece (P=0.042) and Er:YAG laser ( P=0.002) groups.
Cavity preparation by Er:YAG laser and high speed hand piece and bur is not significantly different in terms of microleakage.

Ablative and nonablative lasers have been used to treat melasma. We aimed to assess and compare the combining Q-switched Nd:YAG laser (QSNYL) and fractional erbium:YAG laser (FEYL) with QSNYL alone in treatment of melasma.
This randomized controlled clinical trial was performed in our Research Center during 2013-2014. Women with melasma and without a history of keloid formation, hypersensitivity to hydroquinone, or pigmentary changes due to laser therapy were randomly allocated to receive four sessions of either QSNYL-FEYL combination or QSNYL alone. All patients received topical treatment with Kligman’s formula. Before laser therapy and 4 weeks after the last treatment session, patients’ skin was assessed for changes in skin color, melanin content, and erythema intensity of melasma lesions quantitatively.
Finally, 21 patients in QSNYL-FEYL and 20 in QSNYL group (mean age, 38.57 [5.60] and 42.60 [8.44] years, respectively) completed study. The skin color had become lighter in both groups (mean [SD] percentage change of 56.95 [40.29] and 29.25 [13.20] in QSNYL-FEYL and QSNYL groups, respectively) with significantly better results in QSNYL-FEYL group (P = 0.006). Percentage of decrease of melanin content was significantly higher in QSNYL-FEYL group (22.01 [10.67] vs. 7.69 [4.75]; P QSNYL-FEYL was significantly more effective in decreasing melanin content of lesions than QSNYL and led to a lighter skin.