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عضویت

جستجوی مقالات مرتبط با کلیدواژه « Uterine artery » در نشریات گروه « پزشکی »

  • Berikuly Duman *, Ali Abdulhussain Fadhil, Samah Sajad Kadim, Ayad Abas Hasan, Naseer Mehdi Mohammed, Ebtihal Sattar Qasim, Tamara Muayad Abdullah
    Background &
    Objective
     Preeclampsia is related to numerous maternal and fetal complications, like intrauterine increase restriction, preterm delivery, and a raised danger of baby death. In order to determine the predictive amount of uterine artery Doppler sonography indices for neonatal complications in pregnant patients with preeclampsia, the present study was conducted.Materials &
    Methods
     In 2020, in Alwiyah Hospital for Obstetrics and Gynecology, Al-Jadiriah Private Hospital, Al-Karama Teaching Hospital, and Yarmouk Teaching Hospital in Baghdad, 87 pregnant women with preeclampsia and 160 healthy pregnant women participated in the present prospective study. The Doppler signal of the uterine arteries was evaluated during a supine abdominal Doppler ultrasound examination between 26 and 36 weeks of pregnancy. The survey form was updated with information about the birth of the children following the termination of the pregnancy. The data were evaluated using SPSS software (version 19) and independent t, Mann-Whitney, and chi-square tests.
    Results
     The mean uterine artery pulsatility index of mothers with preeclampsia had the greatest sensitivity, specificity, and positive predictive amount of predicting a baby's low birth weight at 54.8%, 87.3%, and 91.6%, respectively. In addition, the sensitivity, specificity, and positive predictive amount of the mean uterine artery resistance index for predicting a baby's low birth weight were 65.2%, 96.4%, and 95.4%, respectively.
    Conclusion
    Although uterine artery indices in Doppler ultrasound do not have a high sensitivity for predicting neonatal complications, abnormal indices can predict low birth weight with high confidence.
    Keywords: Preeclampsia, Doppler Sonography, Uterine Artery, Complications}
  • پژمان خوارزم، فاطمه پولادخای، طیبه آذرمهر، فرحناز السادات احمدی، فاطمه زهرا باقری*

    خونریزی شدید بعد از زایمان (Postpartum Hemorrhage: PPH) یک اورژانس مامایی غیر قابل پیش بینی و از علل عمده مورتالیتی و عوارض مادری در جهان است. آنوریسم کاذب شریان رحمی (Uterine Artery Pseudoaneurysm: UPA) یکی از علل نادر PPH است که به دنبال سزارین بدون عارضه و جراحی های ژنیکولوژیک مانند دیلاتاسیون و کورتاژ، هیسترکتومی و میومکتومی ایجاد می شود. راه درمانی مناسب برای کنترل خونریزی در این موارد آمبولیزاسیون شریان رحمی است. هدف ما از این گزارش معرفی بیماری با سابقه سزارین است که به دنبال خونریزی شدید رحمی با تشخیص آنوریسم کاذب شریان رحمی به طور موفق تحت آمبولیزاسیون شریان رحمی با استفاده از کویل قرار گرفت. بیمار خانم 39ساله ای بود که 55 روز بعد از عمل جراحی سزارین سوم با شوک همودینامیک در نتیجه خونریزی شدید واژینال، به بیمارستان مراجعه نمود و بستری شد. پس از انجام مراقبت های اولیه، اقدامات تشخیصی UAP را نشان داد و بلافاصله آمبولیزاسیون شریان رحمی به وسیله کویل انجام شد. هرگاه اقدامات نگهدارنده معمول، نتواند خونریزی شدید دیررس بعد از زایمان را کنترل کند؛ آنژیوگرافی و آمبولیزاسیون شریان رحمی روش درمانی انتخابی است که به واسطه آن می توان ضمن حفظ توانایی باروری بیمار، از عوارض بالقوه هیسترکتومی جلوگیری کرد.

    کلید واژگان: آنوریسم کاذب, شریان رحمی, خونریزی شدید بعد از زایمان, آمبولیزاسیون شریان رحمی}
    Pezhman Kharazm, Fatemeh Pouladkhay, Tayebeh Azarmehr, Farahnaz Sadat Ahmadi, Fatemehzahra Bagheri*

    Late postpartum hemorrhage (PPH), as an unpredictable obstetrics emergency, is characterized as a leading cause of mortality and maternal complications worldwide. Uterine artery pseudoaneurysm (UAP) is a rare cause of PPH, which may develop after uncomplicated cesarean and Gynecologic surgeries, including dilatation and curettage, hysterectomy, and myomectomy. Uterine artery embolization has become a popular treatment for postpartum hemorrhage. In this case report, we present a patient with PPH due to UAP who was treated by endovascular embolization of the uterine artery. A 39-years-old woman was admitted 55 days after her third cesarean section due to massive vaginal bleeding resulting in severe hemodynamic derangements. After initial resuscitative measures, diagnostic studies revealed the UAP, and soon after, the coil embolization of the uterine artery was performed. When conservative managements fail to control massive late postpartum hemorrhage, angiography and embolization of the uterine artery can be the modality of choice, rather than hysterectomy (with its potential complications) which preserves the patientchr('39')s fertility.

    Keywords: Aneurysm False, Uterine Artery, Postpartum Hemorrhage, Uterine Artery Embolization}
  • Sedigheh Borna, Shahla Nasrolahi, Shahedeh Khansari*
    Objectives
    Preeclampsia is considered as one of the most important causes of death among pregnant women all around the world. This study aimed to study the predictive value of uterine artery Doppler ultrasonography in the incidence of preeclampsia and the intrauterine growth restriction (IUGR) in pregnant women who attended Fatemieh hospital.
    Materials and Methods
    This study was performed by the prospective cohort method and the statistical population included 108 pregnant women, in their 18-22 weeks of pregnancy, with a singleton pregnancy who referred to the prenatal Fatemieh Hospital of Hamadan during 2013-2016. The uterine artery Doppler ultrasonography was performed and the incidence of IUGR and the occurrence of preeclampsia in the followed pregnancy was evaluated in these patients. Data were analyzed by SPSS 16.0 using the chi-square and Mann-Whitney U statistical tests.
    Results
    The mean difference of pulsatility index (PI) in patients with preeclampsia was statistically significant compared to healthy individuals (P = 0.001). In addition, the mean difference of PI in individuals with infants suffering from IUGR was statistically significant compared with the infants not suffering from the IUGR (P = 0.001). Further, the incidence of preeclampsia and IUGR in women with a bilateral notch in ultrasonography was significantly greater than those of the women with no report of a bilateral notch in ultrasonography (P = 0.001).
    Conclusions
    Therefore, Doppler ultrasonography of the uterine artery has a predictive value in preeclampsia among pregnant women.
    Keywords: Doppler ultrasonography, Uterine artery, Preeclampsia, Intrauterine growth restriction}
  • فریده موحد، شکوه سادات ابوترابی*، حمیده پاک نیت، سعیده عباسی
    هدف
    وجود سطوح کافی پروژسترون و وجود سیستم گردش خون رحمی جفتی کارآمد، دو فاکتور مهم در تداوم حاملگی طبیعی محسوب می شوند. افزایش مقاومت عروقی در شریان رحمی با ایجاد اختلال در خون رسانی به رویان می تواند با عوارض ناگواری از جمله تهدید به سقط همراه باشد.  مطالعه حاضر با هدف بررسی تاثیر تجویز شیاف پروژسترون واژینال بر مقاومت شریان رحمی در زنان باردار مبتلا به تهدید به سقط انجام شد.
    مواد و روش ها
    این مطالعه مداخله ای نیمه تجربی در سال1396-1395 در مرکز آموزشی و درمانی کوثر قزوین انجام شد. 51 زن باردار مبتلا به خونریزی واژینال، با سن حاملگی 12-7 هفته که  جنین زنده تک قلو  و سرویکس بسته داشتند، وارد مطالعه شدند. در ابتدا با انجام  سونوگرافی کالر داپلر، میانگینPulsatility Index (PI)  وResistance Index (RI)  در شریان های رحمی دو طرف تعیین شد. سپس 400 میلی گرم شیاف پروژسترون واژینال به مدت 14روز تجویز گردید. با انجام سونوگرافی داپلر، میانگین PI و RI شریان های رحمی مجددا ثبت و متوسط PI و RI قبل و پس از مصرف شیاف پروژسترون واژینال مقایسه شد.
    یافته ها
    میانگین RI در شریان های رحمی دو طرف قبل از درمان 07/0±68/0 بود که پس از درمان به 08/0±55/0 کاهش یافت (001/0P<). هم چنین میانه PI شریان های رحمی دو طرف قبل از مداخله (48/1 و 05/1) 17/1 بود که پس از دوره درمانی به (14/1 و 77/0) 95/0 تقلیل یافت (001/0P<).
    نتیجه گیری
    تجویز شیاف پروژسترون واژینال با بهبود شاخص های RI و PI سبب کاهش مقاومت شریان رحمی در زنان  مبتلا به تهدید به سقط شد.
    کلید واژگان: پروژسترون, شریان رحمی, سقط خودبخودی, خطر سقط}
    Farideh Movahed, Shokoohosadat Abotorabi*, Hamideh Pakniat, Saeedeh Abbasi
    Introduction
    Adequate levels of progesterone and efficient uteroplacental circulatory system are considered as two important factors in maintaining normal pregnancy. Conspicuously, increased vascular resistance in the uterine artery can lead to severe complications including threatened abortion by an impairment to the embryo’s blood supply. This study was conducted to determine whether vaginal progesterone suppository administration effect on uterine artery resistance in women with threatened abortion.
    Materials and Methods
    This interventional pre-experimental study was done in Kosar hospital of Qazvin (Iran) within 2016-2017. 51 pregnant women with vaginal bleeding were entered in the study who had alive singleton fetus with 7 to 12 gestational age and closed cervix. Initially mean pulsatility index (PI) and resistance index (RI) were determined in uterine arteries on both sides by color Doppler sonography. Then, 400 mg vaginal progesterone suppository was administered for 14 days. Using color Doppler sonography, the mean PI and RI of uterine arteries were recorded again and the mean of PI and RI were evaluated before and after using vaginal progesterone suppository.
    Results
    The mean of RI in uterine arteries on both sides was 0.68±0.07 before treatment and decreased to 0.55±0.08 after treatment (P<0.001). Also before intervention, the median of PI in uterine arteries on both sides was 1.17 (1.05 and 1.48) which decreased to 0.95 (0.77 and 1.14) after treatment (P <0.001).
    Conclusion
    Vaginal progesterone suppository administration reduced uterine artery resistance by improving RI and PI index in women with threatened abortion.
    Keywords: Progesterone, Uterine Artery, Spontaneous Abortion, Threatened Abortion}
  • Mahboobeh Shirazi, Parichehr Pooransari, Fatemeh Rahimi Sharbaf, Shirin Niromanesh, Mamak Shariat, Zeinab Pahlavan, Mahmoud Shirazi, Maryam Ahmadian, Behrokh Sahebdel *
    Background: Antenatal anxiety or maternal stress is a prevalent chronic mental disorder in pregnant women. We have assessed the effect of maternal stress from positive aneuploidy screening results on the changes in uterine artery blood flow. Materials and Methods: We performed a prospective cohort (one sample) pilot study at a hospital in Tehran, Iran. A total of 60 pregnant women who were candidates for amniocentesis due to abnormal sequential screening test results entered the study. We conducted 2 standard psychological tests, the Spielberger’s State-Trait Anxiety Inventory and the Beck Anxiety Inventory, to determine anxiety levels in the participants before amniocentesis and two weeks after amniocentesis. The uterine artery resistance index was also measured before and two weeks after amniocentesis. The level of maternal stress was compared with the uterine artery resistance index. Results: Patients had a mean State Trait Anxiety Inventory score before amniocentesis of greater than 40, which meant that the mothers experienced high anxiety. There were no correlations between both inventories’ anxiety scores and uterine artery blood flow before amniocentesis. However, two weeks after amniocentesis, we observed significant negative correlations between the State Anxiety (P=0.0041) and Trait Anxiety (P=0.010) Inventory scores and the uterine artery resistance indexes. Also, there was an association between the decreased right uterine artery resistance index and State Anxiety scores (P=0.036). There were significant correlations between State and Trait Anxiety scores and second trimester analytes of β-human chorionic gonadotropin (β-hCG, P<0.001), α-fetoprotein (P<0.001), and unconjugated estriol (P=0.048). Conclusion: Maternal anxiety because of positive aneuploidy screening serum analytes and amniocentesis can af- fect perinatal outcomes via mood-based alterations in blood flow of the uterine arteries and the screening markers β-hCG,unconjugated estriol, and α-fetoprotein.
    Keywords: Amniocentesis, Doppler, Prenatal Screening, Stress Disorders, Uterine Artery}
  • مقدمه

    فشار خون بالا ناشی از بارداری (PIH) علت مهم مرگ و میر مادران است. راه مناسب برای کاهش آن، شناسایی عوامل پیش از تولد و زایمان است که خطر ابتلا به پرفشاری خون ناشی از بارداری را مشخص می کند. شکل موج داپلر شریان رحم به یک جریان بالا با مقاومت کم در 22-24 هفته حاملگی تبدیل می شود.

    هدف

    مطالعه عوامل خطرساز مادری و شکل موج داپلر شریان رحم در حاملگی سه ماهه اول و پیش بینی وقوع فشار خون ناشی از حاملگی.

    موارد و روش ها

    این مطالعه آینده نگر شامل بررسی اولتراسوند داپلر شریان رحم 697 زن با حاملگی تک قلویی در هفته 20-23 بارداری که برای اسکن معمول مراجعه کرده بودند انجام شد. PIH در 57 مورد (8/18%) از همه حاملگی ثبت شد.

    نتایج

    سن مادر> 34 سال، تک اولادی، وجود فشار خون مزمن با افزایش خطر ابتلا به PIH همراه بود. شاخص پالسایی بالا (>95th percentile) در مقایسه با شاخص پالسایی پایین یک ابزار خوب برای تشخیص فشار خون ناشی از بارداری (حساسیت 91/23% و ویژگی 99/06%، 0/05>p) بود. حضور پالسایی بالا یک عامل خطر مهم برای ابتلا به PIH زودرس در مقایسه با PIH دیررس بود.

    نتیجه گیری

    داپلر شریان رحمی می تواند به طور ایمن در زمان سه ماهه دوم حاملگی در زمان اسکن معمول برای شناسایی ناهنجاری ها انجام شود. این روش ساده، مقرون به صرفه، قابل اجرا و با نرخ تشخیص خوب است.

    کلید واژگان: فشار خون بالا, پره اکلامپسی, تروفوبلاست, سونوگرافی, داپلر, شریان رحم}
    Nidhi Sharma, Krishnamurthy Jayashree, Kulasekaran Nadhamuni
    Background

    Pregnancy induced hypertension (PIH) is a significant cause of maternal morbidity and mortality. Pregnancy-induced-hypertension can be prevented by identification of prenatal and antenatal factors. The uterine artery Doppler waveform transforms into a high flow with low resistance at 22-24 wk.

    Objective

    To study the maternal risk factors and uterine artery Doppler waveform in singleton mid-trimester pregnancy and predict the occurrence of pregnancy-induced hypertension.

    Materials And Methods

    This is a cohort study comprising of Doppler ultrasound examination of the uterine arteries at 20-23 wk gestation in 697 women with singleton pregnancies attending a routine target scan. The pregnant women were followed up. PIH was recorded in 57 (8.18%) of all pregnancies.

    Results

    Maternal age >34 yr, primiparity, the presence of chronic hypertension was also associated with increased risk of PIH. High pulsatility index (>95th percentile) as compared to low pulsatility index was a good tool for the detection of PIH (sensitivity 91.23% and specificity 99.06%, p

    Conclusion

    Uterine artery Doppler can be safely performed at the time of routine target anomaly scan in the second trimester. It is simple, economical, feasible and with good detection rates.

    Keywords: Hypertension, Preeclampsia, Trophoblasts, Ultrasonography, Doppler, Uterine artery}
  • Sudha Prasad*, Ritu Goyal, Yogesh Kumar, Poonam Nayar, Supriya Hajela, Aswathy Kumaran, Rajesh Vairagi, Shalini Chauhan
    Background
    The purpose of the study was to evaluate the role of uterine blood flow parameters measured by uterine artery two-dimensional (2D)-power color doppler (PCD) ultrasound in predicting fertility outcomes in women undergoing IVF-ET cycles.
    Methods
    In this prospective observational study, a total of 188 infertile women who underwent IVF-ET cycles were investigated. Uterine artery 2D-PD measurements were taken during early follicular phase and on day of trigger. Pulsatility Index (PI), Resistant Index (RI), Peak Systolic Velocity (PSV), and Systolic/Diastolic ratio (S/D) were measured. Statistical correlation was sought between the doppler parameters and fertility outcomes.
    Results
    The pregnancy rate was 40.43% (76/188). The women who conceived (n= 76) (Group A) were found to have mean age of 31.2±3.9 years whereas the nonpregnant group of women (n=112) (Group B) had mean age of 31.45±4.25 years. The mean PI measurements subsequently during early follicular phase and on the day of hCG trigger between group A and group B were comparable (2.09±1.15 versus 1.9±0.95; p=0.385 and 1.86±1.12 versus 2.03±1.0; p=0.192, respectively). No significant changes in the uterine artery PSV values and S/D values and RI were noted during the cycle.
    Conclusion
    Uterine artery doppler evaluation in women undergoing IVF cycles was not predictive of the pregnancy outcomes.
    Keywords: Doppler ultrasound, Follicular phase, IVF-ET, Pregnancy outcomes, Uterine artery}
  • پروانه لایق، ملیحه عافیت، دنیا فرخ، مریم صالحی، زهرا رضوانی مهمویی*، رضا مردانی
    مقدمه
    پره اکلامپسی با عوارض متعدد مادری و جنینی شامل محدودیت رشد داخل رحمی، زایمان پره ترم و افزایش خطر مرگ و میر جنین همراهی داشته و از طرفی به نظر می رسد که افزایش مقاومت در عروق رحمی همراه با افزایش خطر پیشرفت به سمت پره اکلامپسی است. لذا مطالعه حاضر با هدف بررسی ارزش شاخص های سونوگرافی داپلر شریان رحمی در پیش بینی عوارض نوزادی در زنان باردار مبتلا به پره اکلامپسی انجام شد.
    روش کار
    این مطالعه آینده نگر در سال 1393 بر روی 46 زن باردار مبتلا به پره اکلامپسی و 74 زن باردار سالم مراجعه کننده به بیمارستان های امام رضا (ع) و ام البنین (س) مشهد انجام شد. بررسی سونوگرافی داپلر شکمی در هفته های 36-26 بارداری در وضعیت خوابیده انجام شد و سیگنال داپلر از شریان های رحمی مورد ارزیابی قرار گرفت. پس از ختم بارداری اطلاعات مربوط به تولد نوزادان به فرم بررسی اضافه شد. تجزیه و تحلیل داده ها با استفاده از نرم افزار آماری SPSS (نسخه 16) و آزمون های تی دانشجویی، من ویتنی و کای اسکوئر انجام شد. میزان p کمتر از 05/0 معنی دار در نظر گرفته شد.
    یافته ها
    بیشترین حساسیت، اختصاصیت و ارزش اخباری مثبت میانگین شاخص پالستیلیتی شریان رحمی مادران مبتلا به پره اکلامپسی برای پیش بینی وزن کم هنگام تولد نوزاد به ترتیب 7/51%، 9/90% و 7/93% بود. همچنین بیشترین حساسیت و ارزش اخباری مثبت میانگین شاخص مقاومت شریان رحمی برای پیش بینی وزن کم هنگام تولد نوزاد 62% و 7/94% به دست آمد. به علاوه میانگین شاخص مقاومت شریان رحمی در پیش بینی همه نتایج نامطلوب بارداری اختصاصیت بالایی داشت.
    نتیجه گیری
    شاخص های سونوگرافی داپلر شریان رحمی اگرچه دارای حساسیت بالایی برای پیش بینی عوارض نوزادی نیستند، اما در صورت غیر نرمال بودن با اطمینان بالا می توان وزن کم هنگام تولد را برای نوزاد پیش بینی کرد
    کلید واژگان: پره اکلامپسی, سونوگرافی داپلر, شریان رحمی}
    Parvaneh Layegh, Malihe Afiat, Donya Farrokh, Maryam Salehi, Zahra Rezvani Mahmouee*, Reza Mardani
    Introduction
    Introduction
    preeclampsia is associated with various maternal and neonatal outcomes such as intra-uterine growth retardation, preterm labor and increased risk of fetal mortality. It seems that increased uterine vascular resistance is associated with higher risk of preeclampsia progression. This study was performed with aim to investigate uterine artery indexes in Doppler sonography for predicting neonatal outcome in preeclamptic pregnancies.
    Methods
    this prospective study was conducted on 46 pre-eclampsia and 74 normal pregnant women referred to Emam Reza and Omalbanin hospitals in 2014. Trans-abdominal Doppler sonography was conducted between 26-36 weeks of pregnancy at supine position and Doppler signals of uterine artery indexes were evaluated and after delivery, neonatal complications were added to the form of evaluation. Data was analyzed by SPSS software (version 16) and T-student, Chi-square and Mann-Whitney tests. P
    Results
    The highest sensitivity, specificity and positive predictive value for the mean Pulsatility index of uterine artery in women with preeclampsia in predicting of low birth weight infants were 51.7% and 90.9% and 93.7%, respectively. The highest sensitivity and positive predictive value of uterine artery resistance index in predicting of low birth weight infants were 62% and 94.7%, respectively. Also, mean uterine artery resistance index in prediction of all adverse pregnancy outcomes had high specificity.
    Conclusion
    Although uterine artery indexes in Doppler sonography has no high sensitivity to predict neonatal outcomes, but their abnormal range can predict low birth weight.
    Keywords: Doppler sonography, Preeclampsia, Uterine artery}
  • Maliheh Arab*, Behnaz Ghavami, Samaneh Saraeian, Samaneh Sheibani, Fatemeh Abbasian Azar, Seyed-Mostafa Hosseini-Zijoud
    Introduction
    Placenta accreta is an increasingly common complication of pregnancy that can result in massive hemorrhage.
    Case Presentation
    We describe two cases of placenta accreta, with successful conservative management in a referral hospital in Tehran, Iran. In both cases, two procedures were performed: compression suture (B-Lynch) and a perfusion-decreasing procedure (bilateral uterine artery ligation). We also present the results of a narrative literature review.
    Conclusions
    The double B-Lynch and uterine arterial ligation procedure in cases of abnormal placentation might be strongly considered in fertility preservation, coagulopathy, coexisting medical disease, blood access shortage, low surgical experience, distant local hospitals, and no help.
    Keywords: Placenta Accreta, Postpartum Hemorrhage, Uterine Artery, Ligation}
  • نازنین فرشچیان، طراوت فاخری، آرازگل حزبی*
    سابقه و هدف
    سندرم تخمدان پلی کیستیک شایع ترین اختلال اندوکرین در زنان سن باروری می باشد که بررسی RI شریان رحمی و تخمدانی می تواند اطلاعات اضافی و کمک کننده درباره پاتوفیزیولوژی این سندرم ارائه دهد و معیار کمک کننده در موارد مشکوک به این سندرم در سونوگرافی به عنوان معیار تشخیصی باشد. هدف از این مطالعه مقایسه پارامترهای جریان خون شریان رحمی و استرومال تخمدان در بین بیماران سندرم تخمدان پلی کیستیک و زنان سالم است.
    مواد و روش ها
    این مطالعه مقطعی بر روی دو گروه 20 نفری از زنان مبتلا به PCOSو زنان سالم (افراد غیر مبتلا به PCOS) انجام شد. در بررسی های اولیه در هر دو گروه متغیرهای سن، BMI، FSH، LH، شدت هیرسوتیسم و آکنه اخذ شد، سپس توسط سونوگرافی Gray scale و داپلر رنگی حجم تخمدان، RI موج شریان رحمی، RI شریان تخمدانی، میزان و اسکولاریزاسیون عروق استرومای تخمدان اندازه گیری و مقایسه شد.
    یافته ها
    RI موج شریان رحمی هر دو سمت در زنان مبتلا به سندرم تخمدان پلی کیستیک(0/94)به طور معنی داری بیشتر از زنان سالم(0/86)بود (0/001 >p) و RI شریان تخمدانی هر دو سمت در زنان مبتلا به سندرم تخمدان پلی کیستیک(0/65) به طور معنی داری کمتر از زنان سالم(0/71) بود (0/001 >p). میزان واسکولاریزاسیون عروق استرومای تخمدان در زنان مبتلا به سندرم تخمدان پلی کیستیک (45%) بیشتر از زنان سالم (0%)بود (0/001> p).
    نتیجه گیری
    براساس سونوگرافی داپلر رنگی پارامترهای جریان خون شریان رحمی و استرومال تخمدان در زنان مبتلا به سندرم تخمدان پلی کیستیک و زنان سالم متفاوت است.
    کلید واژگان: نشانگان تخمدان پلی کیستیک, سونوگرافی داپلر رنگی, شریان رحمی, شریان تخمدان}
    N. Farshchian, T. Fakheri, A. Hezbi*
    Background And Objective
    Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in reproductive-age women. The assessment of uterine and ovarian artery resistance indices (RI) can provide additional information on pathophysiology of the syndrome, and can be applied as a diagnosis criterion in suspected cases of PCOS. This study aims to compare the parameters of uterine artery blood flow and ovarian stromal artery in PCOS patients and healthy women.
    Methods
    This cross-sectional study was performed on 20 women with PCOS (PCOS group) and 20 healthy women (control group). In the initial evaluations, age, body mass index, levels of follicle stimulating and luteinizing hormones, as well as severity of hirsutism and acne were recorded. Then, ovarian volume, uterine and ovarian artery RI and the rate of vascularization of ovarian stromal arteries were measured and compared with each other using Gray-scale and color Doppler sonography (CDS).
    Findings
    Uterine artery RI on both sides in the PCOS patients (94%) was significantly higher than the healthy women (86%) (p<0.001). Ovarian artery RI on both sides in the PCOS group (65%) was lower than the control group (71%) (p<0.001). The rate of vascularization of ovarian stromal arteries was higher in the PCOS patients (45%), as compared to the healthy women (0%) (p<0.001).
    Conclusion
    According to the CDS findings, ovarian stromal and uterine blood flow parameters were significantly different in the PCOS and control groups.
    Keywords: Color Doppler ultrasound, Ovarian artery, Polycystic ovary syndrome, Uterine artery}
  • Ali Irfan Guzel, Selcuk Erkilinc, Irfan Ozer, Aytekin Tokmak, Ayse Kurt Sahin, Mustafa Ugur
    Background
    We conducted this prospective study to evaluate the prognostic significance of uterine and ovarian artery Doppler velocimetry in clomiphene citrate (CC) cycles.
    Materials And Methods
    A total of 80 patients with unexplained infertility were given 100 mg/day of CC from day 3 to day 7 of their cycles in this current prospective study. On cycle day 3, before administration of CC, each patient underwent Doppler transvaginal ultrasonography. The Doppler velocimetries of the right and left uterine and ovarian arteries were recorded and analyzed in association with demographic and clinical parameters.
    Results
    TheThere were 6 out of 80 patients who became pregnant, the overall pregnancy rate in this population was 7.5% for the current study. The cases were divided into two groups according to whether they became pregnant or not. Demographic characteristics showed no statistically significant differences between these groups (p>0.05). However, the duration of infertility did show statistically significant differences between the groups. Doppler velocimetry was not statistically significantly different between the two groups.
    Conclusion
    Doppler velocimetry of the uterine and ovarian arteries is not a factor in the prognosis for pregnancy in CC cycles.
    Keywords: Clomiphene Citrate, Infertility, Uterine Artery, Ovarian, Doppler Velocimetry}
  • Kavous Firouznia, Hossein Ghanaati, Aliakbar Sharafi, Firouze Abahashemi, Hassan Hashemi, Amir Hossein Jalali, Madjid Shakiba
    Background
    Uterine artery embolization (UAE) is a minimally invasive procedure performed under fluoroscopy for the treatment of uterine fibroids and accompanied by radiation exposure..
    Objectives
    To compare ovarian radiation doses during uterine artery embolization (UAE) in patients using conventional digital subtraction angiography (DSA) with those using digital flat-panel technology..Patients and
    Methods
    Thirty women who were candidates for UAE were randomly enrolled for one of the two angiographic systems. Ovarian doses were calculated according to in-vitro phantom study results using entrance and exit doses and were compared between the two groups..
    Results
    The mean right entrance dose was 1586±1221 mGy in the conventional and 522.3±400.1 mGy in the flat panel group (P=0.005). These figures were 1470±1170 mGy and 456±396 mGy, respectively for the left side (P=0.006). The mean right exit dose was 18.8±12.3 for the conventional and 9.4±6.4 mGy for the flat panel group (P=0.013). These figures were 16.7±11.3 and 10.2±7.2 mGy, respectively for the left side (P=0.06). The mean right ovarian dose was 139.9±92 in the conventional and 23.6±16.2 mGy in the flat panel group (P<0.0001). These figures were 101.7±77.6 and 24.6±16.9 mGy, respectively for the left side (P=0.002)..
    Conclusion
    Flat panel system can significantly reduce the ovarian radiation dose during UAE compared with conventional DSA..
    Keywords: Uterine Artery, Embolization, Therapeutic, Radiation, Angiography}
  • Kaveh Akhtari, Mazdak Razi, Hassan Malekinejad
    Background
    The present study was conducted in order to evaluate the effects of bilateral uterine artery ligation (BUAL) on the ovarian follicular fate, and alterations in carbohydrate, lipid, lipase and serum levels of F9SH, LH, prolactin, estrogen and progesterone.
    Methods
    Twenty-four mature female rabbits divided into two test and control-sham groups. The animals underwent ovariohystrectomy on days 23, 43 and 63 after BUAL. Later serum and tissue samples were processed for histological and biochemical analyses. Two-way ANOVA test was used for statistical analyses and p<0.05 was considered as significant.
    Results
    The ovaries from the case groups exhibited markedly increased atretic follicles, which were characterized by early antrum formation, ooplasmic vacoulation, granulosa cells dissociation and oocyte deformation. Lipid foci were remarkably present in the cytoplasm of oocytes, granulosa and theca cells in BUAL rabbits. Smaller sized atretic follicles showed higher lipid reactions than large ones. The PAS reaction was highly positive in zona pellucida (ZP), basement membrane, granulosa cells and follicular fluid of atretic follicles. Early atresiated follicles showed remarkable reaction sites for lipase. Significant (p<0.05) increase in serum levels of FSH, LH, progesterone, and prolactin was revealed in BUAL rabbits compared to the control group while serum levels of estrogen decreased time-dependently in the test groups.
    Conclusion
    The current study suggests the critical role of the uterine artery in controlling ovulation and follicular growth. Moreover atresia processes might relate to lipid accumulation in the cells along with attenuation of lipase activity.
    Keywords: Atresia, Follicle, Gonadal hormones, Ligation, Uterine artery}
  • Mazdak Razi *, Kaveh Akhtari, Ali Reza Najafpour, Keyvan Abdi, Rasoul Shahrooz, Simineh Shahmohamadloo, Sajad Feyzi, Hadi Cheragi
    Background

    Nowadays it is proofed that the uterine artery plays essential role in follicular growth and/or post parturition hemorrhagic.

    Objective

    This study was conducted to evaluate the effect of Bilateral Uterine Artery Ligation (BUAL) on follicular fate and the probable histochemical changes of the carbohydrate and lipids in the ovaries of rabbits.

    Materials And Methods

    24 mature female rabbits randomized into two test and control-sham groups. Test group subdivided to three groups based on time. Animals in the test group under went to BUAL. The ovaries were processed to histochemical and histomorphometric analyses to evaluate the ratio of lipid carbohydrate and lipase enzyme in follicular cells.

    Results

    The ovaries from test groups exhibited many atretic follicles in various sizes. BUAL significantly (p≤0.05) increased the rate of atresia in the test groups in comparison to the control-sham cases. This situation was progressed by the time. In the test groups lipid reactions were observed more remarkable in the small atretic follicles in comparison to the large atretic follicles. BUAL elevated the reaction sites for lipase enzyme in the early stages of the atresia in the test group.

    Conclusion

    Referring to our results BUAL caused significant (p≤0.05) hypo-ovulation by increasing the atresia. Also increasing lipid foci in the first stages of the apoptotic process caused cytoplasmic lipase enzyme evaluation while the lipase enzyme level was decreased by the advancement of the atresia and decreasing of the biological activities in follicular cells.

    Keywords: Atresia, Carbohydrate, Lipase enzyme, Lipid foci, Ovary, Rabbit, Uterine artery}
نکته
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