جستجوی مقالات مرتبط با کلیدواژه « Waist-To-Height Ratio (WHtR) » در نشریات گروه « پزشکی »

As obesity becomes more prevalent, non-alcoholic fatty liver disease (NAFLD) is also becoming a major worldwide health problem and the most common cause of chronic liver disease. A new obesity classification method based on a composite index which includes both the body mass index (BMI) and the waist-to-height ratio (WHtR) was recently proposed. However, the usefulness of this approach to assess the risk of NAFLD is unclear.

This is a cross-sectional study of 1,276 adult individuals in Dalian, China. The Mann Whitney U test, χ 2 test and t-test were used to compare differences between groups. Binary logistic regression analysis was used to identify independent risk factors. Based on BMI and WHtR tertiles, individuals were divided into five new groups. Spearman correlation and receiver operating characteristic curve (ROC) analyses were performed to compare the NAFLD risk factors among groups based on BMI alone, WHtR alone, or the combination of both indexes.

BMI, waistline circumference (WC), WHtR, alanine aminotransferase (ALT), weight, triglycerides (TG), γ-glutamyl transpeptidase (GGT), serum uric acid (SUA), red blood cell (RBC) counts, hemoglobin levels (HGB), fasting blood glucose (FBG) and aspartate aminotransferase (AST) levels were identified as high risk factors for NAFLD (all AUC > 0.7). Logistic regression analysis suggested that BMI and WHtR were independent predictors of the appearance of NAFLD (the ORs for BMI and WHtR were 1.595 and 4.060E-11, respectively; all P < 0.001). The combination of BMI and WHtR tertiles significantly improved the correlation coefficient and Area under the receiver operating characteristic curve (AUC) for NAFLD risk factors in subjects classified as overweight or obese when compared with either BMI or WHtR alone.

BMI, WC, WHtR, ALT, weight, TG, GGT, SUA, RBC, HGB, FBG, AST were high risk factors for NAFLD. The composite BMI and WHtR index improved body fat classification and the ability to detect individuals with NAFLD risk, offering a more precise method for the early identification of high- and low-risk NAFLD patients

Obesity, as a chronic inflammation, is one of the most important health problems in the world. Increased central obesity is associated with increased inflammation. Diet plays a major role in regulating inflammation. The aim of this study was to investigate the relationship between dietary inflammatory index (DII) and obesity in Tehranian women. This cross-sectional study was performed on 199 women living in District 7 of Tehran. Food intake obtained through a food frequency questionnaire (FFQ) and DII was calculated. Weight, height, body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) were measured or calculated. In the final analysis, the effect of age, level of education, smoking status, and physical activity was controlled. The mean age of the subjects was 37.03 years, and the mean BMI was 27.6 kg/m2. The odds of high WC increased with increasing DII score in the crude model (p=0.01) and decreased significantly in the adjusted model (p=0.04). But there was no significant relationship between DII and other variables of abdominal obesity and general obesity (p>0.05). The study states that by increasing the inflammatory index score of the diet, the chance of developing abdominal obesity (waist circumference) decreases. But this result is not true for other variables of abdominal obesity and general obesity.