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عضویت

جستجوی مقالات مرتبط با کلیدواژه « stimulating » در نشریات گروه « پزشکی »

  • Shahrokh Yousefzadeh, Chabok, Babak Alijani, Mohammadreza Emamhadi, Hamid Behzadnia, Siavash Dehghani, Alireza Razzaghi, Shabnam Golmohammadi
    Background and Aim
    Spinal cord injury (SCI) is one of the worst kinds of traumatic injuries with remarkable social and economic effects on communities.
    Methods & Materials/Patients: In this prospective randomized clinical trial, 122 patients with traumatic spinal cord injury were admitted to Poursina hospital within 48 h of injury to compare G-CSF and high-dose methylprednisolone as neuroprotective therapy.
    Results
    In this study, 122 patients were studied out of which 62 patients were included in the granulociote colony-stimulating factor (G-CSF) group with a mean age of 40.4, and 60 patients in the methylprednisolone group with an average age of 40.10 years. 55 patients (45%) out of 122 patients were completely paralyzed (Grade AIS: A) and 67 (55%) were with incomplete spinal injury (Grade AIS: B, C, D). The average ASIA sensory scores in the two groups were similarly compared in the same time intervals, and p values were 0.7, 0.3, 0.2, and 0.1, respectively . They were not statistically significant.
    Conclusion
    According to the results, the G-CSF was shown to be beneficial in average ASIA motor and sensory scores in the two groups of male patients at six months of onset of G-CSF treatment (p value=0.04) and average ASIA motor scores improvement in the falls subgroup patients also differed significantly within six months of onset of G-CSF treatment (p value=0.03). A multicentre prospective randomized clinical trial to compare the placebo effect with G-CSF protocol's treatment, and also assessment of the cost benefits of the common medical treatment versus G-CSF are n eeded.
    Keywords: Granulocyte, Colony, stimulating, Methylprednisolone, Treatment}
  • Shahrokh Yousefzadeh, Chabok, Babak Alijani, Mohammadreza Emamhadi, Hamid Behzadnia, Siavash Dehghani, Alireza Razzaghi, Shabnam Golmohammadi
    Background and Aim
    Spinal cord injury (SCI) is one of the worst kinds of traumatic injuries with remarkable social and economic effects on communities.
    Methods & Materials/Patients: In this prospective randomized clinical trial, 122 patients with traumatic spinal cord injury were admitted to Poursina hospital within 48 h of injury to compare G-CSF and high-dose methylprednisolone as neuroprotective therapy.
    Results
    In this study, 122 patients were studied out of which 62 patients were included in the granulociote colony-stimulating factor (G-CSF) group with a mean age of 40.4, and 60 patients in the methylprednisolone group with an average age of 40.10 years. 55 patients (45%) out of 122 patients were completely paralyzed (Grade AIS: A) and 67 (55%) were with incomplete spinal injury (Grade AIS: B, C, D). The average ASIA sensory scores in the two groups were similarly compared in the same time intervals, and p values were 0.7, 0.3, 0.2, and 0.1, respectively . They were not statistically significant.
    Conclusion
    According to the results, the G-CSF was shown to be beneficial in average ASIA motor and sensory scores in the two groups of male patients at six months of onset of G-CSF treatment (p value=0.04) and average ASIA motor scores improvement in the falls subgroup patients also differed significantly within six months of onset of G-CSF treatment (p value=0.03). A multicentre prospective randomized clinical trial to compare the placebo effect with G-CSF protocol's treatment, and also assessment of the cost benefits of the common medical treatment versus G-CSF are n eeded.
    Keywords: Granulocyte, Colony, stimulating, Methylprednisolone, Treatment}
  • Abbas Tafakhori, Bahaadin Siroos, Mojdeh Ghabaii, Mohammad Hossein Harirchain, Masih Tajdini, Sushil Kumar Garg
    Hashimoto's encephalopathy (HE) is a rare condition characterized by atypical psychiatric and heterogeneous neurological manifestations such as acute cerebral ischemia, seizure, tremors, myoclonus, psychosis, depression, cognitive disorders, and fluctuating loss of consciousness. Here, a case of 28 year-old man was reported who referred to the emergency department (ED) with different acute neurologic disorders and final diagnose of HE.
    Keywords: Encephalopathy, unconsciousness, cognition disorders, immunoglobulins, thyroid, stimulating, neurologic Manifestations}
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