جستجوی مقالات مرتبط با کلیدواژه "babesia ovis" در نشریات گروه "دامپزشکی"

Studies on the pathogenesis of Babesia ovis infection following blood transfusion of infected blood to sheep with intact spleen and splenectomised sheep showed that all animals developed fever concurrent with a parasitaemia that were occurred within 2-4 days post-inoculation (dpi), clinical signs of disease were severe and included varying degrees of anorexia, listlessness, anaemia, moderate jaundice and haemoglobinuria. In intact animals, the hyperthermia returned to normal on the fourth day after the peak pyrexia and parasitaemia was eliminated within the course of the disease in four cases. However, other cases which had severe clinical signs of the disease were died. The parasitaemia reached a maximum of 7% in splenectomised sheep 7-8 dpi; in animals with intact spleen, the parasitaemia was much lower and reached to a maximum of 1%. In both of the infected groups, the red cell counts, haematocrit and haemoglobin concentration fell soon after the appearance of parasitaemia, reaching their lowest levels simultaneously with the peak parasitaemia. The total leukocyte counts were significantly decreased. The total serum bilirubin levels of the infected group rose above the normal and peaked on 14-16 dpi; the rise in AST, BUN and creatinine levels were slight. The kidneys and lungs were the organs most severely affected by experimental infection with B. ovis. Acute alveolar oedema and infiltration of neutrophils and macrophages in interstitial tissue were present, acute diffuse proliferative glomerulitis, congestion and stasis in glomerular capillaries and acute tubular necrosis were also present.

To evaluate the efficacy of treatment in ovine babesiosis. Design: Experimental study. Animals: Thirty six sheep about 1-2 year -old. Procedure: Thirty six sheep, which were negative for any blood parasites, were selected. The animals were categorized into the splenectomized and unsplenectomized groups and each group into 3 subgroups: control, Diminazen and Imidocarb ones. Babesiosis was induced by intravenous injection of 5.2 x10o infected erythrocytes per animal.When body temperature and parasitemia raise, Diminazen (3.5 mg / kbw) and Imidocarb (1.2 mg / kbw) were administrated to each animal in the corresponding groups. Animals were kept up to day 9 post infection. After clinical manifestations, blood samples were daily collected from each animal and hematological parameters determined. Statistical analysis:t-student test. Discussion and

The results indicated that Diminazen is more effective than Imidocarb. Furthermore, clinical signs and parasites were recurred in the treated sheep with Imidocarb.