جستجوی مقالات مرتبط با کلیدواژه « hepatitis b virus » در نشریات گروه « دامپزشکی »

Shellfishes are significant economic and nutritious seafood amongst people of different countries. Seafood products, particularly shellfish samples, are potential reservoirs of enteric viruses. This research investigated the incidence of RoV, NoV GI and GII, HAV, and HEV in shellfish samples from the Persian Gulf, Iran. One hundred and fifty shellfish samples were collected. RNA extraction and cDNA synthesis was performed using commercial kits. The real-time PCR assessed the presence of enteric viruses in extracted cDNA samples. Thirty-two out of 150 (21.33%) shellfish samples were contaminated with enteric viruses. Prevalence of NoV GI, NoV GII, HAV, and RoV amongst shellfish samples were 8.00%, 11.33%, 1.33%, and 0.66%, respectively. There were no contaminated shellfish samples with HEV. Simultaneous prevalence of HAV and NoV GI and HAV and NoV GII viruses were 0.66% and 0.66%, respectively. Examined viruses had a higher prevalence in shellfish samples collected through the winter season (P < 0.05). Prevalence of HAV, RoV, NoV GI, and NoV GII amongst shellfish samples collected through the winter season was 2.85%, 9.09%, 11.90%, and 20%, respectively. To the best of our knowledge, this is the first report of the incidence of enteric viruses, particularly HAV, NoV GI, NoV GII, and RoV, in shellfish samples from the Persian Gulf, Iran. Shellfish samples may serve as a potential source of enteric viruses for the human population. Therefore, routine viral assessments should be conducted. Completely cooking shellfish samples before consumption can significantly reduce the risk of HAV, RoV, NoV GI, and NoV GII infections. Furthermore, given the export value and importance of shellfish samples, their microbial quality and safety should be routinely monitored.

Lichen planus (LP) is an immune-mediated inflammatory disease affecting the skin, nails, and mucous membranes. Its etiology remains unknown, but there are several well-recognized trigger factors, including viral and bacterial antigens, as well as drugs and metals. The prevalence of hepatitis C virus (HCV) infection is the highest among patients with LP. It has been suggested that HCV may contribute to the development of LP, but the relationship between the two is not fully understood. It is still controversial whether HCV leads to LP directly through replication within infected cells or indirectly through the activation of immunological mechanisms. Molecular studies have identified HCV RNA in samples from patients with LP. An autoimmune theory has also been proposed, given that several studies have identified viral replication and activation of the immune response associated with the synthesis of autoantibodies.

We present a clinical case of a rare morphological form of LP against the background of HCV, clearly illustrating the relationship between these diseases.

The study of the relationship between LP and HCV is necessary to understand the pathogenesis of LP, since this dermatosis is an urgent problem in modern dermato-venerology. Apparently, skin lesions result from an immune response to viral components and are not a direct result of HCV.

Chronic renal failure are caused by impaired kidney function; this organ is essential in the metabolism, filtration, and excretion of compounds. Human hepatitis B virus is common in dialysis patients with chronic renal failure, and chronic kidney disease (CKD) is also associated with anemia in dialysis patients. In this study, 50 (36 men and 14 women) dialysis patients from Imamian Al-Khademian city, with ages between 30 and 77 years, and a healthy group (control group) with ages ranging between 30 and 62 years, were evaluated. Detection of hepatitis B virus by a molecular technique of real-time PCR and the concentration of erythropoietin hormone detected by the ELISA technique. The results showed that the prevalence of dialysis patients aged 41–50 and 60–51 was 20% and 18%, respectively. The detection of Hepatitis B from the serum of dialysis patients' samples showed that HBV was seen in 15 (30%) of the 50 serum samples. The concentration of the erythropoietin hormone in dialysis patients’ samples was lower than in the healthy groups (a control group). Also, the concentration of erythropoietin hormone was significantly lower in dialysis patients compared with the control group (P>0.05). Hepatitis B can affect chronic renal failure and dialysis patients' immunity. Also, people with hepatitis B have a lower level of the erythropoietin hormone, which is a major cause of anemia in dialysis patients.