جستجوی مقالات مرتبط با کلیدواژه « peroxidation » در نشریات گروه « دامپزشکی »

According to various effects of probiotics, prebiotics, and symbiotic on production and growth of broiler chicks which was reported, the aim of this study was to investigate the effect of probiotics and prebiotics and a mixture of them, on antioxidant levels and lipid peroxidation index in the blood of Japanese quail. Thus, 192day- old- Japanese quail were distributed randomly to 4 groups with 4 replicates of 12male and female and evaluated for 42days. The control group only received basal diet, but the 2nd group (probiotic group) active saccharomyces cerevisiae 1 gr/Kg of feed, in 3rd group (prebiotic group) inactivated saccharomyces cerevisiae 0.5gr/Kg-feed of feed, and in 4th group (synbiotic group) 0.5 gr/Kg saccharomyces cerevisiae and 250mg/Kg-feed inactivated saccharomyces cerevisiae was added to basal diet. Results indicated mean serum levels of Malondialdehyde (MDA) was different statistically in males of group (p<0.05). Also the MDA levels was highest in 4th group and was different statistically in comparison to 3rd group (prebiotic) that have lowest MDA (p<0.05). Total antioxidant capacity (TAC) of plasma was not different statistically in studied groups (p>0.05). On the other hand, Feed consumption and body weight mean in 2nd and 3rd groups was increased in compare to control group and and FCR was decreased significantly in comparison to control and synbiotic group. The best carcass efficiency was in prebiotic group. The results showed used probiotic and prebiotic was effective in performance of Japanese quails, but has not any specified effects on serum-MDA and plasma-TCA.

In the present study, we aimed to study the effect of different concentration of vitamin C (100-3000 micromolar), in vitro, on the membrane integrity and motility of bull spermatozoa in presence of iron (ferrous) ions as lipid peroxidation (LPO) promoter. LPO is one of the manifestations of reactive oxygen species (ROS) attack in biological membranes. LPO impinges on membrane integrity, triggers inactivation of membrane bound enzymes which involve in sperm motility. Vitamin C in the concentration below 1000 micromol protects spermatozoa from free radical damages as evidenced from improvement in their membrane integrity (data of LPO test and HOST) and motility.Concomitantly, there is also witnessed depletion of malondialdehde (MDA) (an end product of LPO) generation following vitamin C supplementation. Vitamin C at 1000 micromol concentration and above, however, is not protective, as evidenced by abrupt fall in sperm membrane integrity (increase in MDA levels and decrease in number of swollen sperm cells) and motility. Collectively, Vitamin C acts as a double-edged sword in different concentrations and researchers must keep in mind this negative side effect of this vitamin application in their research fields like in vitro fertilization/IVF, cell culture, and preservation of gametes.