Evaluation of treatment effect of anti-tuberculosis drugs on the quality of life among tuberculosis patients admitted in Imam Khomeini hospital in Tehran

Despite the possibility of curing TB with medical therapy، it has a sizable impact on the lives of afflicted patients. This study aimed to evaluate of treatment effect of anti-tuberculosis drugs on the quality of life on tuberculosis patients admitted in Imam Khomeini hospital in Tehran. The investigation was a before and after study. It was done in 2006-2007 by fill in Persian translated questionnaire of WHOQOL- BREF on 46 pulmonary or extra pulmonary TB infected patients. Paired samples T-test was performed to find out the differences. After 8 weeks of treatment، mean score elevation was significant in physical (15. 76±23. 89، p<0. 001)، psychological (7. 84±17. 57، p=0. 004)، and social (6. 83±19. 48، p=0. 02) domains. It was not significant in environmental domain (2. 15±8. 48، p=0. 09). Mean score elevation at the discharge time in physical، psychological، social and environmental domains were: (5. 65±16. 56، p=0. 09)، (11. 69±19. 22، p=0. 001)، (1. 04±8. 60، p=0. 41)، and (4. 37±17. 77، p=0. 1)، respectively. In our study، after treatment of tuberculosis، patient’s physical، psychological and social -not environmental- domains of quality of life were elevated، but at the discharge، there was a significant elevation in physical and psychological domains. These results emphasize the importance of patient’s treatment at the first days of admission، with special attention to social and environmental domains.