Evaluation of coronary artery disease and Helicobacter pylori infection

Today، chronic infections are known as a risk factor of Coronary Artery Disease (CAD) and Helicobacter pylori is the most common chronic infection in human all over the world. We tried to understand and recover relationship between H. Pylori infection and CAD. A case-control study conducted on CAD patients admitted in Besat hospital in Tehran. Control group included patients visited hospital in study time without CAD history and gastrointestinal complaint. Each group contained 282 patients and we assessed serum anti H. Pylori Ab level among them. Mean age in our study was 58 years and 58% of them were man. Overall، 63% of CAD patients were seropossitive for H. Pylori versus 33% in control group. (OR: 3. 48، 95% CI: 2. 47-4. 9) Based on our findings H. Pylori infection is most prevalent in patients with CAD and must be known as a risk factor of CAD.