Investigation of antibacterial activity of methanolic extract of Pistacia vera epicarp

Nowadays, increasing antibiotic resistant in bacterial strains, identification and introduction of antimicrobial compounds with herbal origin is very important. Vast area of our country gardens has allocated by Pistacia vera. In this study antibacterial activity of methanolic extracts of Pistacia vera epicarp was studied in vitro condition. In this study methanolic extract of Pistacia vera epicarp provided by maceration method. The antibacterial activity of extract was evaluated against: Staphylococcus epidermidis, Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes, Pseudomonas aeruginosa, Bacillus subtilis, Escherichia coli, Proteus vulgaris, by agar diffusion method (disc & well) and broth dilution methods. The extract of Pistacia vera epicarp prevents the growth of bacteria. The MICs effects of methanolic extract were distinguished against positive bacteria as Enterococcus feacalis with 60 µg/µl. and against gram negative bacteria as Pseudomonas aeruginosa was observed by 62.5 µg/µl. The methanolic extract of pistachio green hull contains antibacterial compounds that prevents the growth of gram-positive and Gram-negative bacteria. The Iranian Pistacia vera epicarp, which indicate the presence of active components can be used as a source of cheap and accessible for medicinal purposes.