Effect of Time of Day on Plasma CRP and IL-6 levels after an Exhaustive Exercise in Healthy Female Subjects

The aim of this study was to investigate the effect of time of day on plasma CRP and IL- levels after an exhaustive exercise in healthy female subjects. Forty-four female physical education college students (mean±SD: age 21.59±1.24 yrs, body mass index 21.11±2.7 kg/ m2) divided in 2 experimental and 2 control groups. Experimental groups performed the Bruce treadmill maximal test after 12 hours fasting in 8 AM and 6 Pm. Blood samples were collected from an antecubital vein before and immediately after the test. Data was analyzed by two way ANOVA test (P≤0.05). Two-way ANOVA revealed that afternoon exercise led to significantly reduce in CRP levels (P=0.008) and morning and afternoon exercise led to signifycantly reduce in IL-6 Levels (P≤0.05). It seems that afternoon high intensity exercise is better and more safe than morning high intensity exercise.