Effect of 12 Weeks Walking on Inflammatory Factors in Postmenopausal Women with Breast Cancer

The aim of this study was to investigate the effect of 12 weeks walking on inflammatory factors in postmenopausal women with breast cancer.

nineteen postmenopausal women with breast cancer with range age of 50 to 65 years (55.05±2.7) who received surgery, chemotherapy and radiation therapy with current hormone therapy by letrozol were randomly divided into two groups; (Control:8, experimental:11).Subjects in the experimental group were performed 12 weeks exercise training program which consisted of 25 to 45 minutes of walking with intensity of %45 -%65 of THR, three times a week. The control group did not participate in exercise training. In pre and post tests, CRP, IL-6, TNF-, anthropometric variables (body weight, BMI, WHR), body fat percentage and Vo2peak were measured in both groups. Data were analyzed through analysis of covariance (ANCOVA) and t test (P<0.05).

The results of this study showed that Vo2peak, body weight and BMI had significant differences between the experimental and control groups, after 12 weeks (P<0.05). There is no significant differences between CRP, IL-6, TNF-, WHR and body fat percentage, in both groups (P>0.05). After 12 weeks, body weight was decreased in the experimental group and was increased in control group; BMI was decreased in the experimental group and was increased in control group. Also, VO2peak was increased in the experimental group and was decreased in control group.

It can be concluded that 12 weeks walking there have no effect on inflammatory factors in postmenopausal women with breast cancer, but may improve VO2peak, body weight and BMI.