Antinociceptive effect of hydroalcoholic extract of green tea in male mice
Author(s):
Abstract:
Background
The use of medicinal plants due to their lower side effects and the various efficient components has been increased in recent years. The aim of this study was to evaluate the antinociceptive effect of hydroalcoholic extract of green tea in male mice using the hot plate and formalin tests. Materials And Methods
In this experimental study، 56 NMRI male mice (weight، 28±3 g) were assigned to the control and experimental groups. The experimental group received the green tea extract (75، 150 and 300 mg/kg) and 30 min after the injection، the hot plate and formalin tests were used to assess the acute and chronic pain. Results
Results showed that hydroalcoholic extract of green tea (75mg/kg) could induce antinociception in phase 2، not in phase 1 and interphase of the formalin test. Hydroalcoholic extract of green tea (150 and 300 mg/kg) could also induce antinociception in phase 1، interphase and phase 2 of the formalin test. Moreover، hydroalcoholic extract of green tea caused a delay on the painful behaviors in hot-plate test. Conclusion
Hydroalcoholic extract of green tea has analgesic properties and can be used as a substitute for chemical analgesic drugs.Keywords:
Language:
Persian
Published:
Feyz, Volume:17 Issue: 6, 2014
Pages:
528 to 536
magiran.com/p1228950
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!