The effect of 4 weeks resistance training on plasma omentin-1 concentrations in diabetic rats

The purpose of this study was to investigate the effect of 4 week resistance training on plasma omentin-1 levels in Streptozotocin induced diabetic rats. In this experimental study 24 male Wistar rats with mean weight of 288±22g (mean±SD) were randomly divided into 3 groups: non-diabetic control (n=8)، diabetic control (n=8)، and diabetic training (n=8). Diabetes was induced by a single intra-peritoneal injection of streptozotocin (STZ) at a dose of 55 mg/kg. The resistance training consisted of climbing a ladder carrying a load suspended from the tail (3 days/wk، for 4 wk). After 4-week body weight، plasma omentin-1، glucose، insulin، non-esterified fatty acids (NEFA) concentrations and lipid profiles were measured. After four weeks plasma omentin-1 levels in trained diabetic rats was higher when compared with diabetic control group، but it was not statistically significant. We did not find any significant difference in plasma glucose، insulin، NEFA and lipid profile levels between all groups. Body weights alteration in diabetic resistance trained rats were significantly lower compared with the diabetic control group. The results of this study indicated that plasma levels of glucose، insulin، lipid profile and omentin-1 remained unchanged in diabetic rats due to 4 weeks resistance training. Short duration of training program appears to be an effective factor in the absence of significant changes in plasma omentin-1 levels.