Survey on the Eradication of Helicobacter Pylori Infection in Quadruple Therapy:Amoxicillin, Bismuth, Omeprazole and Clarithromycin

Helicobacter Pylori infection is one of the most common infectious diseases.It can result in chronic gastritis, peptic and duodenal ulcers, MALT lymphoma and gastric cancer. The H-pylori infection can lead to a wide range of diseases and the cost spent on the eradication is much less than the cost spent on the treatment of complications of the infection Study the efficacy of quadruple therapy (Amoxicillin, Bismuth, Omeprazole and Clarithromycin) on the eradication of Helicobacter Pylori infection. Between March 2011 and December 2011, we conducted a Quazi- experimental study on Helicobacter pylori infectious patients in Anzali. They were included after doing an endoscopy. Eight weeks after taking four-drugs regimen, Urea Breath Test was done to check the rate of eradication. The majority of the patients were females (58.7 %). The most common symptoms before the treatment were flatulence (76 %) and epigastric pain (74.9 %). The eradication rate was 89.9 %. There were significant differences in all of the symptoms while the difference between gender and eradication rate was non-significant. Regardless of few side effects, all symptoms of the patients were treated significantly. As the eradication rate was 89.9 %, this quadruple drug regimen was effective on the eradication of the H-pylori. Conflict of interest: non declared