Evaluation of correlation of high sensitive CRP with bioelectrical impedance parameters in patients undergoing hemodialysis

the aim of the study was to evaluate the relationship between high sensitive CRP (hs-CRP) and bioelectrical impedance parameters in patients undergoing hemodialysis (HD).

This study was conducted on 38 patients undergoing HD since September of 2012. Bioelectrical impedance parameters including total body fat, fat free body, total body water (TBW),intra and extra cellular water(ICW and ECW), ECW/ICW and phase angle (PA) were measured. Serum hs-CRP was measured and Body Mass Index (BMI) was computed. Pearson`s correlation analysis was used to find out any correlation among variables.

A total of 38 patients (15 males and 23 females) with age of 48.58 ± 16 years were included in this study. The mean length of hemodialysis treatment was 46.34 ± 48.33 months. There was no correlation between hs-CRP and TBW, ICW, ECW and ECW/ICW and PA. There was a significant positive correlation between hs-CRP and total body fat and an inverse correlation with fat free body. We also observed a significant positive correlation between hs-CRP and BMI.

he results showed a significant positive correlation between hs-CRP and total body fat and an inverse correlation with fat free body in patients undergoing HD which showed the probable role of increasing body weight as well as total body fat on inflammation process in HD patients. Acknowledgment: his article is adapted from thesis 901160 for receiving national board of Internal Medicine specialty of Dr Mansoureh Hoseinzadeh. This study was supported by the Kidney transplantation Complications Research Center and a grant from Mashhad University of Medical Sciences.