Induction of growth and proliferation of fibroblast cells in magnetic field

Message:
Abstract:
Background
Tissue engineering is generally defined as developing and changing the laboratory growth of molecules and cells in tissues or organs to replace and repair the damaged part of body. This study was carried out to stimulate the growth of cultured fibroblast cells by a physical electromagnetic method.
Methods
First، an air-core coil was prepared and the cell culture plate was placed comfortably into the mold، then the plate containing the culture medium and human fibroblast cell along with air-core coil were placed in an incubator and then connected to the power supply. Thus، the sample underwent electromagnetic field at different times، and cell proliferation was studied byMTTassay.
Results
Microscopic images indicated that the cells undergoing electromagnetic field (0. 3 amps) had a significant growth compared to the cells in control group in a definit range of stimulation.
Conclusion
In conclusion، electromagnetic stimulation in a definite range led to cell proliferation and could be used as a positive factor in tissue engineering.
Language:
Persian
Published:
Journal of Kermanshah University of Medical Sciences, Volume:18 Issue: 11, 2015
Pages:
612 to 618
https://magiran.com/p1380091  
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