Investigating the effect of calcium sulfate on liver hemorrhage control in an animal model

The control of parenchymal hemorrhage especially in liver parenchyma, despite surgical science progresses is still one of the challenges surgeons face saving the patients’ lives and there is a research challenge between the researchers in this field to introduce a more effective method. This study aimed to determine the hemostatic effect of calcium sulfate on controlling the bleeding from liver parenchymal tissue. In this animal model study 60 male Wistar rats were used. A length of two cm and a depth of half a cm incision were made on each mouse’s liver and the hemostasis time was measured using calcium sulfate different concentrations (5%, 10%, 15%, 25%, and 50%) and the control method (i.e. control of bleeding by suturing). Finally, the obtained data were entered into SPSS software and analyzed using Kruskal-Wallis test and Mann-Whitney, Kolmogorov-Smirnov. The hemostasis time of calcium sulfate concentration groups was significantly less than that of the control group (p<0.01). Calcium sulfate is an effective hemostatic agent in controlling liver parenchymal tissue hemorrhage in an animal model.