Vitamin E and Omega-3, 6 and 9 Combinations Versus Vitamin E in the Treatment of Mastodynia

Breast pain or mastodynia is moderate to severe pain, which affects around 22 - 41% of women. If no anomaly is found and other causes, like nutritional changes, are excluded, many drugs, including herbal supplements, are recommended for the treatment of mastodynia.. This study was performed to evaluate the effects of vitamin E and omega-3, 6 and 9 free fatty acids combinations versus Vitamin E in women with mastodynia..Patients and A double blind, randomized clinical trial was conducted in Shohada Ashayer Hospital in Khorramabad Lorestan province, in the vest of Iran. A total of 88 women with symptoms of mastodynia, aged between 20 - 55 years old, were divided to two groups. The patients were randomly assigned to receive vitamin E (400 U/day) and vitamin E (400 U/day) plus omega-3, 6 and 9 (1200 mg/day) orally, for 3 months.. Vitamin E plus omega free fatty acids are more effective than the use of vitamin E alone in decreasing mastodynia. Significant difference was seen between the Cardiff Breast Score (CBS) of the vitamin E group compared to vitamin E - omega group (P < 0.05) at the end of the first, second and third months after treatment.. Our results showed that vitamin E plus omega free fatty acids decrease the severity of mastodynia better than vitamin E alone..