Treatment of severe axillary Hyperhidrosis with Botulinum toxin A

Severe axillary hyperhidrosis causes considerable emotional stress to individuals affected with this condition. Existing topical and surgical therapies are either ineffective or associated with unacceptable morbidity and sequelae.

In this study we attempted to determine the effect of botulinum toxin A (Dysport) in the treatment of axillary hyperhidrosis. Patients and

After visualization of hyperhidrosis using the iodine-starch test, ten patients with axillary hyperhidrosis underwent intradermal injection with 125 units of Dysport in the axillary skin bilaterally. Patients were observed for 7 months after treatment.

The treatment was well tolerated without side effects. All patients experienced relatively complete anhidrosis of the axillary skin after about one week for periods lasting from 4 to 7 months.

Botulinum-A toxin may offer a fast, safe, and highly effective therapeutic option for severe hyperhidrosis.