The effect of combined aerobic- resistance training on lipid profile and liver enzymes in patients with non-alcoholic fatty liver under nutrition diet

The purpose of this study was to determine the effects of combined aerobic-resistance training on lipid profile and liver enzymes in patients with non-alcoholic fatty liver disease under diet. 19 male patients (age: 38.1±8.2 years and BMI of 28.1±3.8 Kg/m2) were randomly divided into two groups of diet and diet plus exercise intervention. Training program included combination of aerobic (50-70 Percent of HRR) and resistance training (50-70 percent of 1RM), eight weeks and three sessions per week. In order to designing dietary regimen, alleviate 400 to 500 kcal/day from total daily calorie intake. Before and after intervention, blood taking, body composition, maximal oxygen consumption, and muscular strength assessment performed. Data were analyzed using dependent and Independent-Samples T test on gain scores, employing the SPSS 18 statistical package program (α≤0.05). The results indicated significant improvement in maximum oxygen uptake (P= 0.0001), and reduction in body composition indexes, TC (P= 0.0001), TG (P= 0.01), LDL (P= 0.004) and TC/HDL (P= 0.0001) in both diet and combined exercise group. In diet group, a considerable improvement was observed in weight (P= 0.01), body mass index (P= 0.01), waist circumference (P= 0.004), waist to hip ratio (P= 0.04), maximum oxygen uptake (P= 0.0001), TC (P= 0.01), LDL (P= 0.005) and TC/HDL (P= 0.003). But between group differences were not significant. This study showed that eight weeks of diet alone and combined with diet have no significant effect on liver enzymes in non alcoholic fatty liver patients, but induce increase in maximal oxygen consumption and improvement in lipid profile in patients with non alcoholic fatty liver. However, there is not significant difference between two groups. Insufficient period of intervention (diet and exercise), frequency and intensity of training may be the possible causes of ineffectiveness of exercise and diet on above-mentioned variables.