Investigation of the gasoil inductive effects on liver parameters of white albino NMRI Mice

Message:
Abstract:
Since Gasoil due to the aromatics of the most important environmental pollutants and is one of the oil with many applications. According to its damaging effects on living organisms and human beings, the purpose of this study was to investigate the effects of Gasoil on the parameters of liver, white rat race was Albino NMRI. The 40 mice in 4 groups, adult male mice were divided into control and treatment of adult female rats were divided into control and treatment, with an average weight of 28 grams divided and studied. In mice treated for 14 days and every day, once 0.2cc Pure fuel-grade solution 6.6 mg/kg mice were fed weight. After anesthesia and studies macroscopic and microscopic slides prepared from liver tissue parameters, using software and the death a measure of statistical analysis software was SPSS19. Studies in male and female treatment groups compared to the control group in the parameters of liver tissue, represents the mean diameter of lobular central vein, sinusoid, the core of the cell to the cell surface and the number of single-core and dual-core to reduce the diameter of the vein between lobular that these changes in level (P<0.05) were significant. Gasoline is causes these changes because the aromatic compounds and create free radicals in the liver. Thus, according to its various applications, notification should be done on ways to deal with complications and to reduce its effects.
Language:
Persian
Published:
Quarterly Journal of Experimental Animal Biology, Volume:4 Issue: 3, 2016
Pages:
79 to 90
https://magiran.com/p1498860  
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