Known pathophysiological mechanisms in the incidence of varicoceles

Varicocele is characterized by dilation and abnormal tortuosity of the spermatic veins in testes and it has long been implicated as a major cause of treatable in fertile men. Testicular function in individuals with varicocele progressively damaged but the exact mechanisms involved in initiation and development of dysfunction of testis in these individuals are not fully known. Therefore, the aim of this review article was to study known pathophysiological mechanisms in the incidence of varicocele.
Literature search in different electronic databases such as Science Direct, Pubmed and Scopus, as well as other data sources were related to ISI between 1989-2015.
Varicocele is often associated with abnormal spermatogenesis, elevated testicular temperature and oxidative stress. This condition is lead to reduction of semen quality and fertility.
The microsurgical varicocelectomy method is now the preferred approach between most urologists due to low recurrence rates and complications compared to other treatment suggested by urologists.