The Effect of hordeum vulgare L. on the development of lung tissues in the embryo of diabetic albino rats

The goal of this research is to see how barley grains affect the development of lung tissues in the embryo of diabetic albino rats. An empirical study was done on 60 albino rats in four groups: 1. Control, 2. Healthy barely diet, 3. Diabetic normal food, 4. Diabetic barely diet. A peritoneal injection of streptozotocin was used to develop diabetes in the rats. In the 21st day of pregnancy the embryos were removed from the uterine horns, weighed and measured from head to tail. After tissue processing, H&E staining was done and the embryos’ lung tissues were analyzed using an optical microscope. The diabetic normal food group showed less development in bronchioles, alveoli and pneumocyte compared to the control group and had hyperemic vessels and the most inflamed alveolar interstitial tissue. The diabetic barely group had more developed bronchioles, alveoli and pneumocyte compared to the diabetic normal food group. This group has fewer hyperemic vessels and inflamed alveolar interstitial tissue compared to the diabetic normal food group. The embryos in the diabetic normal food increased in weight while the diabetic barely group had a slight decrease in weight.However, the decrease in weight was not significant. The head to tail length of the embryos in the diabetic normal food decreased compared to the control group and barely had no effect on the head to tail length in the diabetic barely group. It seems that barely is beneficial on the development of lung tissues in the embryo of diabetic albino rats. Barely can regulate the excess weight caused by diabetes to some extent; however, it has no effect on the reduction of head to tail length caused by high glucose.