A rapid, easy, and efficient method for synthesis of 4,4'-(arylmethylene)-bis-(1H-pyrazol-5-ols), catalyzed by boehmite nanoparticles

Author(s):

Mohammad Bakherad* , Ali Keivanloo , Amir H. Amin , Rahele Doosti , Zahra Aghayan

Message:
Abstract:
An efficient and eco-friendly method is introduced for the synthesis of 4,4'-(arylmethylene)-bis-(1H-pyrazol-5-ols) by the condensation reaction of two equivalents of 5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one with various aromatic aldehydes, catalyzed by the boehmite nanoparticles (BNPs). This heterogeneous catalyst was recycled and used in four runs for the reaction between benzaldehyde and 3-methyl-l-phenyl-5-pyrazolone without any loss of its catalytic activity.
Keywords:

Heterogeneous catalyst , Aldehyde , One , pot reaction , 3 , Methyl , l , phenyl , 5 , pyrazolone

Language:
English
Published:
Journal of Applied Chemistry Today, Volume:11 Issue: 41, 2016
Pages:
31 to 38
https://magiran.com/p1571114