Frequency of Polymorphism Alu Insertion in Progesterone Receptor Gene in Endometriosis

This research aimed to study a possible link between endometriosis and polymorphism of the progesterone receptor gene.
The control group consisted of 86 women without endometriosis and the case group comprised 86 patients with a diagnosis of endometriosis by laparoscopy. Genotypes for Alu insertion polymorphisms (A1/A1, A1/A2 and A2/A2) were described by polymerase chain reaction and determined on a 2% agarousegel.
The genotype frequencies of A1/A2 and A2/A2 were not significantly higher in patients than in the control group without endometriosis. On the other hand differences in the Alu insertion polymorphism frequencies were not significant.
According to our investigations, we conclude that there is not a significant correlation between Alu insertion polymorphism and endometriosis. ;line-height:115%'> According to our investigations, we conclude that there is not a significant correlation between Alu insertion polymorphism and endometriosis.