The effect of injection of vitamins A and E on passive transfer of immunoglobulin G and some blood parameters in calf

Increasing of colostrum immunoglobins absorption is an important factor in calf health. Vitamin A and vitamin E reserves are low in calf and colostrum feeding don’t significantly increase them. According to possibility deficiency of these vitamins, their role in epithelium health including intestine mucosa and improvement of immune status this study was conducted to investigate the effect of injection vitamins A and E on passive transfer of immunoglobulin G, total protein, AST enzyme ad some hematologic factors of calves.
Material and The 12 newborn female Holstein calves were on a randomized complete design experiment with four treatments consisting of three replications. Treatments were included: treatment Control: injection of 14% of body weight of normal saline; treatment vitamin A: injection of 200000 IU vitamin A; treatment vitamin E: injection of 300 IU of vitamin E and treatment vitamin A: injection of 200000 vitamin A 300 IU vitamin E, immediately after birth and before colostrum feeding. Colostrum was harvested from first lactations and freezed. After injection, colostrum was fed about 10% body weight. Blood samplings were conducted from the jugular vein at pre-injection and days three, 14 and 28 post-injection. The serum IgG concentration was measured by ELISA method. Hematologic factors including total protein, AST, hemoglobin, hematocrit, blood cell count including platelet, RBC, WBC and RBC indices were measured.
Immunoglobin Data analyzed at randomized complete design and other data analyzed with repeated measure design using SPPSS v.21.
There was significant difference in serum blood immunoglobulin G between treatment vitamin A and vitamin E (P single injection of 200000 IU vitamin A and 300 IU vitamin E had no significant effect on serum IgG and other hematologic indices.