Effect of Aqueous and Alcoholic Extracts of Roots of Ferula Gummosa Boiss on Growth of Some Bacterial Pathogens

Introduction and Aims Because of the day-increasing resistance of the bacteria to antibiotics, further logical viewpoint to the medicinal plants seems to be important. The Ferula gummosa considered as a great medicinal plant in past studies. The aim of this study was investigation of aqueous and alcoholic extracts of roots of F.gummosa Boiss on growth of some bacterial pathogens.
Materials and Methods The extracts were prepared by Soxhlet method and were studied by disc diffusion, well diffusion and tube dillution methods.
Results According to the disc diffusion and the well diffusion methods, no inhibitory zone have seen against investigated bacteria. The ethologic extract showed more inhibitory effect than the methanolic and aquatic extracts. The most sensitive bacterium to methanol extract was Staphylococcus aureus with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) equal to 6.25×103 and 1.25×104 respectively. The most sensitive bacteria to ethanol extract were Escherichia coli and Shigella dysenteriae with MIC and MBC equal to 6.25×103 and 2.5×104 respectively.
Conclusion Further study is needed about potent antimicrobial activities of F.gummosa Boiss.