Immunity Evaluation of Razi Newcastle (LaSota) and Infectious Bronchitis (H-120) Live Bivalent Vaccine

Newcastle and infectious bronchitis are causes severe economic losses in poultry industry. Control of these two important poultry disease is based on biosecurity procedures and vaccination. The objective of this study was to evaluate potency of live combine Newcastle (La-Sota) infectious bronchitis (H-120) vaccine in commercial broilers, in compare with their monovalent vaccine. Five hundred commercial broiler chickens were divided into four groups including three 150 bird treatment groups and one 50 bird (control) group. Chickens in group A were vaccinated with each of Newcastle La-Sota and infectious bronchitis H-120 vaccine, group B was received live combine Newcastle (La-Sota) infectious bronchitis (H-120) Razi vaccine. Chickens in group D were vaccinated with the commercial combine vaccine. Antibody titers against Newcastle and infectious bronchitis viruses were evaluated by haemagglutination inhibition (HI) and serum neutralization (SN) assay, respectively on collected sera at defined times. Chickens in groups A and B had sufficiently specific antibody levels against both viruses. There were no significant differences between body weight and feed consumption between treatment and control groups. Razi Newcastle (LaSota) Infectious bronchitis (H-120) live combine vaccine induces high levels of specific antibody against both viruses by one-time administration.