Evaluation of serum Malondialdehyde level in patients with oral lichen planus

Message:
Abstract:
Introduction
Malondialdehyde (MDA) is a useful determinant to show high level of lipid peroxidation which lead to impaired cell function. Previous studies have mentioned there is a relationship between high oxidative stress and low anti-oxidant activity in patients with oral lichen planus. The aim of this study was to evaluate serum level of Malondialdehyde as an indicator of oxidative stress in patients with oral lichen planus which is a chronic inflammatory disease with unknown etiology.
Materials and Methods
This descriptive-comparative study evaluated the oxidative stress status on twenty patients with oral lichen planus and 20 control healthy individuals based on serum level of Malondialdehyde.
Results
The mean serum Malondialdehyde levels in oral lichen planus patients and control individuals were 2.9 (±2) and 2.4 (±1.3) µg/ml, respectively, indicating no significant difference (P=0.6).
Conclusion
According to the results, role of Malondialdehyde in cellular damage and pathogenesis of oral lichen planus was not proved.
Language:
English
Published:
Caspian Journal of Dental Research, Volume:6 Issue: 1, Mar 2017
Pages:
45 to 48
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