The Effect of Premedication on Anxiety and Vital Signs of Patients Undergoing Coronary Angiography in Ganjavian Hospital, Dezful, Iran

Coronary angiography is one of the most common diagnostic procedures in heart disease that similar to other invasive procedures, it is a stressful experience for the patients. This article aimed to determine the effect of premedication on anxiety and vital signs of the patients undergoing coronary angiography.
This is a single-blind clinical trial, that 102 patients were enrolled as the sample using convenience sampling through the random allocation (three 34-member groups). Data were collection tools include: demographic questionnaire, Self-Report Anxiety Scale, and Vital Signs Scale. In premedication group A (100 mg hydrocortisone and 4 mg intravenous chlorpheniramine premedication), In premedication group B(100 mg intravenous hydrocortisone and 5 mg intravenous diazepam), In premedication group C(100 mg hydrocortisone and 2 mg intravenous normal saline) were given. Statistical analysis was performed using SPSS software.
The results showed that in all three premedication, statistically significant difference was found in terms of anxiety before and during the angiography(p0.05). The comparison of systolic and diastolic blood pressure showed a statistically significant difference in all three groups (p Some the research findings show the influence of diazepam and chlorpheniramine the variables under study, which is advisable if needed. It is also recommended, because of the cost and complications of the premedication before coronary angiography is unnecessary in some cases.