Feasibility of Biological Effective Monitoring of Chrome Electroplaters to Chromium through Analysis of Serum Malondialdehyde
Author(s):
Abstract:
Background
Great concern about occupational exposure to chromium (Cr [VI]) has been reported due to escalated risk of lung cancer in exposed workers. Consequences of occupational exposure to Cr (VI) have been reported as oxidative stress and lung tissue damage.Objective
To investigate the feasibility of biological effect monitoring of chrome electroplaters through analysis of serum malondialdehyde (MDA).Methods
90 workers directly involved in chrome electroplatingcategorized into three equal groups based on their job as near bath workers, degreaser, and washersand 30 workers without exposure to Cr (VI), served as the control group, were studied. Personal samples were collected and analyzed according to NIOSH method 7600. Serum MDA level was measured by HPLC using a UV detector.Results
Median Cr (VI) exposure level was 0.38 mg/m3 in near bath workers, 0.20 mg/m3 in degreasers, and 0.05 mg/m3 in washers. The median serum MDA level of three exposed groups (2.76 μmol/L) was significantly (pConclusion
Serum MDA level is a good biomarker for the level of occupational exposure to Cr (VI) in electroplaters.Keywords:
Language:
English
Published:
International Journal of Occupational and Environmental Medicine, Volume:7 Issue: 4, Oct 2016
Pages:
199 to 206
https://magiran.com/p1696898
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