Evaluation of Invitro Antifungal Activity of Mentha Piperita and Carum Capticum Against Saprolegnia Parasitica

Saprolegniasis is an important aquatic fungal disease that causes severe damages at different growth stages of aquatic animals. The aim of this study was to measure the minimum inhibitory concentration (MIC) of alcoholic and aqueous extracts of Carum capticum and Mentha piperita on Saprolegnia parasitica. The antifungal activity of the aqueous, ethanolic and methanolic extracts of M. piperita and C. capticum on S. parasitica was tested using a mycelial radial growth technique and minimal inhibition concentration values were estimated according to the micro dilution method. The results of antifungal activity by mycelia radial growth technique showed that the ethanolic extract of M. piperita had a significant antifungal activity (MIC=10mg/ml) compared with the other extracts against S. parasitica. The growth potential in S. parasitica increased with increase in the concentration. Growth inhibition values of plant extracts on S. parasitica in broth micro dilution method were not significant (MFC ≥ 2048). Our study suggests that natural products derived from the examined medicinal plants have the potential to be used as antifungal in fish culture.