Effect of Omega-3 on Plasma Levels of Homocysteine and Fibrinogen Following a Single Session of Circuit Resistance Training in non-athlete Obese Women

Elevated plasma levels of homocysteine and fibrinogen are considered cardiovascular risk factors. The aim of the present study was to investigate the effects of short-term supplementation of omega-3 on homocysteine and fibrinogen levels in response to a single session of circuit resistance training in non-athlete obese women.
In a quasi-experimental research with a pretest-postest design, 20 non-athlete women with body mass index ≥30 kg/m2 participated as subjects. The participants were divided randomly into two equal groups of 1) placebo and 2) omega-3 supplement. The training intervention consisted of a single session of circuit resistance training at nine stations with intensity of 40% 1RM at the end of one week omega-3/placebo supplementation, consumed orally, 3 capsules (each containing 3000 mg) per day for one week. Blood samples were collected in two phases before and after the resistance training. Plasma levels of homocysteine and fibrinogen were assayed using ELISA methods, and data were analyzed using ANCOVA test (p There was a significant difference between the groups at in their postest values of homocysteine (p=0.0001) and fibrinogen (p=0.0001). The omega-3 supplement group showed less increase in the research variables.
It is concluded that short-term consumption of the omega-3 supplement may be useful in preventing increase in homocysteine and fibrinogen levels in response to a single session of circuit resistance training in non-athlete obese women.