Optimization of Porous Structures Based on Polypropylene Fumarate /Hydroxy Ethyl Metacrylate/ Bioactive Glass Prepared by Biomimetic Methods with Mechanical Strength and Surface Morphology Analyses

This work is related to optimize the porous structure nanocomposites based on polypropylene fumarate/ hydroxyethyl methacrylate/ bioactive glass nanoparticles (PPF/HEMA/NBG) which are cross-linked through the Reduction-Oxidation reaction (free radical polymerization) at the room temperature. The porous structures prepared by immersion of the nanocomposites in simulated body fluid (SBF) for 4 weeks. The samples were optimized based on the PPF/HEMA ratio, the NBG content and percentage of the benzoyl peroxide and dimethyl aniline pairs (BPOೀ) with mechanical strength (compressive strength) and surface morphology (SEM images) analyses. Finally, the best structure based on mentioned factors, SPHB.732/1.5, which contains the PPF/HEMA ratio at 30/70, NBG content at 20 wt% and BPOೀ pairs at 1.5 wt% was introduced as the optimum structure. This structure has an elastic modulus of 57.7 Mpa, interconnected-open porous architecture with the pore size approximately 100-200?m and the surface coated with hydroxycarbonate apatite microparticles (HCA). The SPHB.732/1.5 structure prepared by soaking in SBF not only is a bioactive component but also is a biodegradable material and hence can be used as a bone scaffold when more evaluate for this application.