Comparison of the Effect of Adding Dexmedmodine and Fentanyl to Bupivacaine on the Adequacy of Anesthesia and Postoperative Pain in Lumbar Discectomy under Spinal Anesthesia

This study aimed to compare the effect of adding dexmedmodine and fentanyl to bupivacaine on the adequacy of anesthesia and postoperative pain in lumbar discectomy under spinal anesthesia.
In a clinical trial study, 105 patients who candidate for lumbar discectomy in Kashani hospital in Isfahan, Iran, during the years 2016-17 were selected and randomly divided into three groups of 35 patients. For the spinal block, in the first group, 15 mg Marcaine plus 25 µg/kg fentanyl, in the second group 15 mg Marcaine plus 50 µg/kg dexmedetomidine, and in the third group, 15 mg Marcaine alone was were injected. The adequacy of anesthesia and postoperative pain was compared between the groups during and after the surgery.
Findings: The mean postoperative pain in the three groups of Marcaine fentanyl, Marcaine dexmedmotidine and Marcaine alone was 5.09 ± 1.5, 4.14 ± 1.1, and 4.89 ± 1.5 (P The use of the combination of dexmedmotidine and Marcaine in patients undergoing lumbar disc surgery with local anesthesia is accompanied by a reduction in the appropriate postoperative pain, and a greater satisfaction of the patient and the physician.