Effect of Aerobic Exercise with Maximal Fat Oxidation Intensity, on Adropin and Insulin Resistance among Overweight Women

Adropin plays an important role in lipid metabolism; however, no research seems to have been done on the effect of exercise on serum adropin levels. Therefore, the present study attempted to investigate the effect of an aerobic exercise session with FATmax intensity on adropin levels and insulin resistance among overweight women.
The participants, who volunteered to take part in the research through announcements, included 24 overweight women with the means and standard deviations of their age, height, and weight being 25.34±4.1 y, 163.6±4.07 cm, and 76.94±4.56 kg, respectively. The exercise group performed an acute endurance activity, while the control group rested for the same amount of time. In an acute endurance activity session, the participants ran on treadmills for 30 minutes at their FATmax intensities. Changes in the data for the two groups were calculated, before and after the activity session and then compared using independent-samples t-tests. The significance level for all the statistical analyses was set at p Results showed significant differences between the two groups in terms of insulin (p=0.030) and insulin resistance (p=0.031), but not such a difference for glucose (p=0.327) and adropin (p=0.330). It seems that this type of activity, despite its largely aerobic nature, simply failed to stimulate adropin, due to the effect of the control group’s fasting state on increasing adropin levels, and/or the lower duration and intensity of the activity