The Frequency and Risk Factors of Delayed Graft Function in living Donor Kidney Transplantation and Its Clinical Impact on Graft and Patient Survival in Part of Middle East

Delayed graft function (DGF) is a form of acute renal failure which results in increased post-transplantation allograft immunogenicity and risk of rejection episodes in addition to decreased long-term survival. Its incidence and risk factors have been extensively studied, especially after deceased donation. However until now, only few data has been published on DGF in living donor kidney transplant recipients. The present study was performed to investigate the frequency and risk factors of DGF among living- kidney transplant recipients.

In this retrospective study, 500 living kidney transplant recipients recruited and data collected from hospital registries in three countries (Iran, Kingdom of Saudi Arabia (KSA) , and Kuwait ).

Incidence of DGF revealed to be %95) %2.3 CI: %3.6-%0.9). DGF group showed significant older age for the recipients and in “without DGF” group, there were more females, and lower weight for the recipients. It was found that patients with DGF had longer pre transplant dialysis duration, cold ischemic and anastomosis time during surgery .

DGF after living-donor kidney transplantation is a multifactorial complication which donor, recipient, and technical factors would lead toward. Consideration and optimization of these risk factors may drive through better long-term patient and graft outcomes in living kidney transplant recipients.