The effects of eight weeks of aerobic exercise and resveratrol supplementation on oxidative stress markers in women with metabolic syndrome

The aim of the present study was to investigate the effects of eight weeks aerobic exercises and resveratrol supplementation on oxidative stress markers in women with metabolic syndrome.

A double-blind study was carried out with participation of 32 overweight women with metabolic syndrome. The participants were randomly categorized into four groups of aerobic exercise, resveratrol supplement, and exercise plus the supplement and control. The exercise protocol was eight weeks long with three 60 min sessions every week. The supplement and placebo used in the study were 400 mg/day. The malondialdehyde and total antioxidant capacity serum levels were measured at the beginning and end of the study.

The results of statistical analysis showed that the eight weeks aerobic exercise led to a significant decrease in malondialdehyde and a significant increase in total antioxidant capacity in the exercise, exercise plus supplement, and resveratrol supplement groups compared to control group with greater effect in exercise plus supplement group.

Using resveratrol supplement along with aerobic exercises can be effective in attenuating oxidative stress. Further studies with larger sample size are needed to confirm these results.