A Review on Analytical Methods of Antigout Agents

The aim of this study was to provide information of the development in analytical perspective of impurityprofiling,force degradation,and bioanalysis of pharmaceutical drug substance,drug products used forthe treatment of gout. This information was discussed on the basis of year of publication,matrix (activepharmaceutical ingredient,dosage form,and biological fluid),sample preparation technique,column andtypes of elution in chromatography (isocratic or gradient),detector,and therapeutic categories of drug,which were used for analysis. It focuses mainly on analytical methods including hyphenated techniques forthe identification,quantification of impurity,degradants,and metabolites in different pharmaceuticaland biological matrices.