Sudden Increase of Antipsychotics and Induction of Deep Vein Thrombosis

Antipsychotics (APs) can induce pathological blood clotting. Deep Vein Thrombosis (DVT) is a common type of Venous Thromboembolism (VTE) and a significant cause of morbidity and mortality worldwide. First or second generation APs have been specifically correlated with an increased risk of thromboembolism.

We report a case of a bipolar female patient who developed DVT following an increase in her daily dose of APs (olanzapine and chlorpromazine).

Physicians in other medical fields, including internal medicine and surgery, should be trained about the complication of DVT induced by APs.