Prognostic Factors of Outcome in Methanol Poisoning; an8-year Retrospective Cross-sectional Study

Identification of high-risk patients with poor prognosis is essential for quick diagnosis and treat-ment of methanol poisoning to prevent death and improve the outcome. The aim of this study was to evaluatethe clinical and laboratory factors in patients with methanol poisoning to determine the prognosis and outcome.

In this retrospective cross-sectional study, all patients with methanol poisoning, who had presentedto the emergency department of Tohid Hospital, Sanandaj, Iran from 2011 to 2019 (8 years) were enrolled usingcensus method. Multivariate logistic regression analysis was performed to find the independent predictive fac-tors of poor outcome in the mentioned patients.

Methanol poisoning was diagnosed in 52 (11.55%) ofthe 450 cases admitted to hospital for alcohol intoxication. In multivariate analysis, time interval from methanolintake to hospital admission (OR=1.06; 95% CI= 1.00-1.11; p=0.04), respiratory arrest (OR=25.59; 95% CI= 1.37-478.13; p=0.03), and higher concentration of blood glucose (OR=1.03; 95% CI= 1.00-1.09; p=0.03) had a signif-icant correlation with Poor outcomes.

Based on the findings of this study, delayed admission tohospital, respiratory arrest and hyperglycemia were identified as independent risk factors of poor outcome inmethanol poisoning.