Traumastem Powder in Treatment of Non-Traumatic Anterior Epistaxis in Emergency Department; a Randomized Clinical Trial

Various studies are being conducted because of the value of finding an appropriate medication tocontrol bleeding in patients with epistaxis faster and more conveniently. This study aimed to compare the effectof Traumastem powder with routine tampons in treatment of non-traumatic epistaxis.

This random-ized clinical trial enrolled patients with epistaxis presenting to the emergency departments of two hospitalsaffiliated to Tabriz University of Medical sciences. Patients were divided into two groups using randomizationsoftware (intervention group: 107 patients, control group: 96 patients). Primary outcome variables includedbleeding control time and patient satisfaction. Secondary outcome variable was recurrence of bleeding withinthe first 24 hours after treatment. Visual assessment scoring system was used to assess patient satisfaction.Re-sults:Epistaxis was controlled in less than 5 minutes in 85 (79.4%) patients in the intervention group and 85(88.5%) patients in the control group (P=0.058). Patient satisfaction in the intervention group was higher thanthat of the control group (P<0.05). In the intervention group, 10 patients experienced recurrence of epistaxiswithin 24 hours of treatment, while 9 patients in the control group experienced recurrence (P= 0.591).Conclu-sion:Based on the findings, bleeding control time was similar in the two groups, but patient satisfaction washigher in Traumastem group. It is concluded that Traumastem can conveniently control anterior epistaxis, butit is not successful in cases with severe bleeding